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Extracellular Vesicles [PDF]

GENETICS
Abstract Extracellular vesicles (EVs) encompass a diverse array of membrane-bound organelles released outside cells in response to developmental and physiological cell needs. EVs play important roles in remodeling the shape and content of differentiating cells and can rescue damaged cells from toxic or dysfunctional content. EVs can send
Qian Wang, Lei Zheng
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Understanding extracellular vesicles [PDF]

PROTEOMICS, 2021
No description ...
David W. Greening, Richard J. Simpson
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Investigating the consistency of extracellular vesicle production from breast cancer subtypes using CELLine adherent bioreactors

Journal of Extracellular Biology, 2022
Extracellular vesicle (EV) research has grown rapidly in recent years, largely due to the potential use of EVs as liquid biopsy biomarkers or therapeutics.
Colin L. Hisey, Anastasiia Artuyants, George Guo, Vanessa Chang, Gabrielle Reshef, Martin Middleditch, Bincy Jacob, Lawrence W. Chamley, Cherie Blenkiron   +8 more
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Dosing extracellular vesicles

Advanced Drug Delivery Reviews, 2021
Extracellular vesicles (EVs) are natural nanoparticles containing biologically active molecules. They are important mediators of intercellular communication and can be exploited therapeutically by various bioengineering approaches. To accurately determine the therapeutic potential of EVs in pre-clinical and clinical settings, dependable dosing ...
Gupta, Dhanu, Zickler, Antje Maria, El Andaloussi, Samir   +2 more
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SnapShot: Extracellular Vesicles

Cell, 2020
Cells release a variety of extracellular vesicles (EVs; including exosomes, microvesicles, and many others) into their environment. EVs can bud in endosomes or directly at the plasma membrane, carrying a selection of components from the cell and displaying various functional properties.
Cocozza, Federico, Grisard, Eleonora, Martin-Jaular, Lorena, Mathieu, Mathilde, Théry, Clotilde   +4 more
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Inhalable exosomes outperform liposomes as mRNA and protein drug carriers to the lung

Extracellular Vesicle, 2022
Respiratory diseases are among the leading causes of morbidity and mortality worldwide, coupled with the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Kristen D. Popowski, Blanca López de Juan Abad, Arianna George, Dylan Silkstone, Elizabeth Belcher, Jaewook Chung, Asma Ghodsi, Halle Lutz, Jada Davenport, Mallory Flanagan, Jorge Piedrahita, Phuong-Uyen C. Dinh, Ke Cheng   +12 more
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Extracellular Vesicles—Connecting Kingdoms [PDF]

International Journal of Molecular Sciences, 2019
It is known that extracellular vesicles (EVs) are shed from cells of almost every type of cell or organism, showing their ubiquity in all empires of life. EVs are defined as naturally released particles from cells, delimited by a lipid bilayer, and cannot replicate. These nano- to micrometer scaled spheres shuttle a set of bioactive molecules.
Eric Woith, Gregor Fuhrmann, Matthias F. Melzig   +2 more
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Fibroblast-Derived Extracellular Vesicles Induce Colorectal Cancer Progression by Transmitting Amphiregulin

Frontiers in Cell and Developmental Biology, 2020
Extracellular vesicles (EV), structures surrounded by a biological membrane, transport biologically active molecules, and represent a recently identified way of intercellular communication.
Ádám Oszvald, Zsuzsanna Szvicsek, Márton Pápai, Andrea Kelemen, Zoltán Varga, Tamás Tölgyes, Kristóf Dede, Attila Bursics, Edit I. Buzás, Edit I. Buzás, Edit I. Buzás, Zoltán Wiener   +11 more
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Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma

Extracellular Vesicle, 2022
Dysregulated Myc signaling is a key oncogenic pathway in glioblastoma multiforme (GBM). Yet, effective therapeutic targeting of Myc continues to be challenging.
Amanda R. Haltom, Wafa E. Hassen, Janine Hensel, Jiha Kim, Hikaru Sugimoto, Bingrui Li, Kathleen M. McAndrews, Meagan R. Conner, Michelle L. Kirtley, Xin Luo, Bingqing Xie, Olga V. Volpert, Susan Olalekan, Natalia Maltsev, Anindita Basu, Valerie S. LeBleu, Raghu Kalluri   +16 more
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Expanding the horizon of EV-RNAs: LncRNAs in EVs as biomarkers for disease pathways

Extracellular Vesicle, 2023
Extracellular vesicles (EVs) are membrane-bound nanoparticles with different types of cargo released by cells and postulated to mediate functions such as intercellular communications. Recent studies have shown that long non-coding RNAs (lncRNAs) or their
Michail Spanos, Priyanka Gokulnath, Emeli Chatterjee, Guoping Li, Dimitrios Varrias, Saumya Das   +5 more
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