Results 1 to 10 of about 319,764 (352)

Improved Characterization of EV Preparations Based on Protein to Lipid Ratio and Lipid Properties. [PDF]

, 2015
In recent years the study of extracellular vesicles has gathered much scientific and clinical interest. As the field is expanding, it is becoming clear that better methods for characterization and quantification of extracellular vesicles as well as ...
A Biro, A de Gassart, A Kasal, A Llorente, A McMahon, AM Booth, Andrea Balogh, Andrea Caporali, Andrea Németh, B György, B György, B György, Barbara Sódar, Bence György, C Adami, C Bissig, C Kahlert, C Thery, C Thery, DM Owen, E Chabrol, E van der Pol, Edit Irén Buzás, EI Buzas, F Momen-Heravi, GT Szabo, J Holmgren, János Matkó, K Al-Nedawi, Katalin Szabó-Taylor, Krisztina Pálóczi, L Turiak, M Aatonen, M Record, R Crescitelli, R Lacroix, R Lacroix, RO Bilyy, SS Tan, Tamás Géza Szabó, WL Dean, Xabier Osteikoetxea, Z Varga, Ágnes Kittel, Éva Pállinger   +44 more
core   +14 more sources

Investigating the consistency of extracellular vesicle production from breast cancer subtypes using CELLine adherent bioreactors

Journal of Extracellular Biology, 2022
Extracellular vesicle (EV) research has grown rapidly in recent years, largely due to the potential use of EVs as liquid biopsy biomarkers or therapeutics.
Colin L. Hisey, Anastasiia Artuyants, George Guo, Vanessa Chang, Gabrielle Reshef, Martin Middleditch, Bincy Jacob, Lawrence W. Chamley, Cherie Blenkiron   +8 more
doaj   +1 more source

Inhalable exosomes outperform liposomes as mRNA and protein drug carriers to the lung

Extracellular Vesicle, 2022
Respiratory diseases are among the leading causes of morbidity and mortality worldwide, coupled with the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Kristen D. Popowski, Blanca López de Juan Abad, Arianna George, Dylan Silkstone, Elizabeth Belcher, Jaewook Chung, Asma Ghodsi, Halle Lutz, Jada Davenport, Mallory Flanagan, Jorge Piedrahita, Phuong-Uyen C. Dinh, Ke Cheng   +12 more
doaj   +1 more source

Fibroblast-Derived Extracellular Vesicles Induce Colorectal Cancer Progression by Transmitting Amphiregulin

Frontiers in Cell and Developmental Biology, 2020
Extracellular vesicles (EV), structures surrounded by a biological membrane, transport biologically active molecules, and represent a recently identified way of intercellular communication.
Ádám Oszvald, Zsuzsanna Szvicsek, Márton Pápai, Andrea Kelemen, Zoltán Varga, Tamás Tölgyes, Kristóf Dede, Attila Bursics, Edit I. Buzás, Edit I. Buzás, Edit I. Buzás, Zoltán Wiener   +11 more
doaj   +1 more source

Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma

Extracellular Vesicle, 2022
Dysregulated Myc signaling is a key oncogenic pathway in glioblastoma multiforme (GBM). Yet, effective therapeutic targeting of Myc continues to be challenging.
Amanda R. Haltom, Wafa E. Hassen, Janine Hensel, Jiha Kim, Hikaru Sugimoto, Bingrui Li, Kathleen M. McAndrews, Meagan R. Conner, Michelle L. Kirtley, Xin Luo, Bingqing Xie, Olga V. Volpert, Susan Olalekan, Natalia Maltsev, Anindita Basu, Valerie S. LeBleu, Raghu Kalluri   +16 more
doaj   +1 more source

Expanding the horizon of EV-RNAs: LncRNAs in EVs as biomarkers for disease pathways

Extracellular Vesicle, 2023
Extracellular vesicles (EVs) are membrane-bound nanoparticles with different types of cargo released by cells and postulated to mediate functions such as intercellular communications. Recent studies have shown that long non-coding RNAs (lncRNAs) or their
Michail Spanos, Priyanka Gokulnath, Emeli Chatterjee, Guoping Li, Dimitrios Varrias, Saumya Das   +5 more
doaj   +1 more source

Guidelines for clinical translation and commercialization of extracellular vesicles and exosomes based therapeutics

Extracellular Vesicle, 2023
Extracellular vesicles (EVs) are lipid-bilayer delimited membrane structures released by cells, and play a role in intercell communication and disease development. The Global market for EVs in diagnostic and therapeutic applications is expanding.
Ke Cheng, Raghu Kalluri
doaj   +1 more source

Three method-combination protocol for improving purity of extracellular vesicles [PDF]

, 2020
Extracellular vesicles (EVs) are nanosized structures able to carry proteins, lipids and genetic material from one cell to another with critical implications in intercellular communication mechanisms.
Giamas, Georgios, Kumaran, Anish, Simon, Thomas, Veselu, Diana-Florentina   +3 more
core   +1 more source

Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons. [PDF]

, 2015
Disrupting particular mitochondrial fission and fusion proteins leads to the death of specific neuronal populations; however, the normal functions of mitochondrial fission in neurons are poorly understood, especially in vivo, which limits the ...
Berthet, A, Diaz-Ramirez, LG, Gill, TM, Haddad, D, Kim, H, Lam, M, Mucke, L, Nakamura, K, Pathak, D, Ponnusamy, R, Sesaki, H, Shields, LY, Zhu, L   +12 more
core   +7 more sources

Extracellular vesicles, ageing, and therapeutic interventions [PDF]

, 2018
A more comprehensive understanding of the human ageing process is required to help mitigate the increasing burden of age-related morbidities in a rapidly growing global demographic of elderly individuals.
Neytchev, Ognian, Panagiotou, Nikolaos, Selman, Colin, Shiels, Paul G.   +3 more
core   +1 more source