Results 11 to 20 of about 206,828 (334)

An extracellular vesicle delivery platform based on the PTTG1IP protein

Extracellular Vesicle
Extracellular vesicles (EVs) are promising therapeutic delivery vehicles, although their potential is limited by a lack of efficient engineering strategies to enhance loading and functional cargo delivery.
Carla Martin Perez, Xiuming Liang, Dhanu Gupta, Emily R. Haughton, Mariana Conceição, Imre Mäger, Samir EL Andaloussi, Matthew J.A. Wood, Thomas C. Roberts   +8 more
doaj   +2 more sources

Investigating the consistency of extracellular vesicle production from breast cancer subtypes using CELLine adherent bioreactors

Journal of Extracellular Biology, 2022
Extracellular vesicle (EV) research has grown rapidly in recent years, largely due to the potential use of EVs as liquid biopsy biomarkers or therapeutics.
Colin L. Hisey, Anastasiia Artuyants, George Guo, Vanessa Chang, Gabrielle Reshef, Martin Middleditch, Bincy Jacob, Lawrence W. Chamley, Cherie Blenkiron   +8 more
doaj   +1 more source

Coarse-Grained Molecular Simulation of Extracellular Vesicles Squeezing for Drug Loading [PDF]

https://pubs.rsc.org/en/content/articlelanding/2023/cp/d3cp00387f, 2022
In recent years, extracellular vesicles such have become promising carriers as the next-generation drug delivery platforms. Effective loading of exogenous cargos without compromising the extracellular vesicle membrane is a major challenge. Rapid squeezing through nanofluidic channels is a widely used approach to load exogenous cargoes into the EV ...
arxiv   +1 more source

Improved Characterization of EV Preparations Based on Protein to Lipid Ratio and Lipid Properties. [PDF]

, 2015
In recent years the study of extracellular vesicles has gathered much scientific and clinical interest. As the field is expanding, it is becoming clear that better methods for characterization and quantification of extracellular vesicles as well as ...
A Biro, A de Gassart, A Kasal, A Llorente, A McMahon, AM Booth, Andrea Balogh, Andrea Caporali, Andrea Németh, B György, B György, B György, Barbara Sódar, Bence György, C Adami, C Bissig, C Kahlert, C Thery, C Thery, DM Owen, E Chabrol, E van der Pol, Edit Irén Buzás, EI Buzas, F Momen-Heravi, GT Szabo, J Holmgren, János Matkó, K Al-Nedawi, Katalin Szabó-Taylor, Krisztina Pálóczi, L Turiak, M Aatonen, M Record, R Crescitelli, R Lacroix, R Lacroix, RO Bilyy, SS Tan, Tamás Géza Szabó, WL Dean, Xabier Osteikoetxea, Z Varga, Ágnes Kittel, Éva Pállinger   +44 more
core   +5 more sources

Three method-combination protocol for improving purity of extracellular vesicles [PDF]

, 2020
Extracellular vesicles (EVs) are nanosized structures able to carry proteins, lipids and genetic material from one cell to another with critical implications in intercellular communication mechanisms.
Giamas, Georgios, Kumaran, Anish, Simon, Thomas, Veselu, Diana-Florentina   +3 more
core   +1 more source

Center-Periphery Structure in Communities: Extracellular Vesicles [PDF]

Quantitative Science Studies (2022), 2021
Clustering and community detection in networks are of broad interest and have been the subject of extensive research that spans several fields. We are interested in the relatively narrow question of detecting communities of scientific publications that are linked by citations. These publication communities can be used to identify scientists with shared
arxiv   +1 more source

Multiscale Dynamics of Lipid Vesicles in Polymeric Microenvironment [PDF]

Membranes 2022, 12(7), 640, 2022
Understanding dynamic and complex interaction of biological membranes with extracellular matrices plays a crucial role in controlling a variety of cell behavior and functions, from cell adhesion and growth to signaling and differentiation. Tremendous interest in tissue engineering has made it possible to design polymeric scaffolds mimicking the ...
arxiv   +1 more source

Extracellular vesicles, ageing, and therapeutic interventions [PDF]

, 2018
A more comprehensive understanding of the human ageing process is required to help mitigate the increasing burden of age-related morbidities in a rapidly growing global demographic of elderly individuals.
Neytchev, Ognian, Panagiotou, Nikolaos, Selman, Colin, Shiels, Paul G.   +3 more
core   +1 more source

Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes [PDF]

, 2013
Introduction: In recent years, there has been an exponential increase in the number of studies aiming to understand the biology of exosomes, as well as other extracellular vesicles.
Berent-Maoz B, Chaput N, Choi DS, Cocucci E, Droin N, Ekström K, Escola JM, Freyssinet JM, György B, Johnstone RM, Kalra H, Keller S, Lehmann BD, Lespagnol A, Lässer C, Lässer C, Mathivanan S, Rajendran L, Ratajczak J, Simpson RJ, Stoorvogel W, Suliman A, Théry C, Turiák L, Valadi H, van der Pol E, van der Pol E, van Niel G, Yu X   +28 more
core   +2 more sources

Machine Learning Characterization of Cancer Patients-Derived Extracellular Vesicles using Vibrational Spectroscopies [PDF]

Applied Intelligence (2022), 2021
The early detection of cancer is a challenging problem in medicine. The blood sera of cancer patients are enriched with heterogeneous secretory lipid bound extracellular vesicles (EVs), which present a complex repertoire of information and biomarkers, representing their cell of origin, that are being currently studied in the field of liquid biopsy and ...
arxiv   +1 more source