Results 11 to 20 of about 236,767 (310)

Guidelines for clinical translation and commercialization of extracellular vesicles and exosomes based therapeutics

Extracellular Vesicle, 2023
Extracellular vesicles (EVs) are lipid-bilayer delimited membrane structures released by cells, and play a role in intercell communication and disease development. The Global market for EVs in diagnostic and therapeutic applications is expanding.
Ke Cheng, Raghu Kalluri
doaj   +1 more source

Extracellular Vesicles in Neuroinflammation [PDF]

Frontiers in Cell and Developmental Biology, 2021
Extracellular vesicles (EVs) are a heterogenous group of membrane-bound particles that play a pivotal role in cell–cell communication, not only participating in many physiological processes, but also contributing to the pathogenesis of several diseases.
Marostica G., Gelibter S., Gironi M., Nigro A., Furlan R.   +4 more
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Greasing wheels of cell-free therapies for cardiovascular diseases: Integrated devices of exosomes/exosome-like nanovectors with bioinspired materials

Extracellular Vesicle, 2022
Mortality and morbidity of cardiovascular diseases (CVDs) including ischemic heart disease (IHD) and heart failure (HF) are arising worldwide. Once cardiomyocyte is impaired, it is challenging to regenerate which is largely limited by the irreversibility
Xuerui Chen, Liyun Zhu, Jianyun Liu, Yi Lu, Longlu Pan, Junjie Xiao   +5 more
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The interactions between extracellular vesicles and mesenchymal stem cells: Their potential roles in osteoarthritis development and cartilage repair

Extracellular Vesicle, 2022
Osteoarthritis (OA) is a chronic cartilage degeneration disease affecting total joint and with a wide global impact. Stem cell therapy has emerged as a potential stock for the treatment of OA.
Qiong Yang, Danyang Yue, Qian Ren, Guoqing Xia, Baihui Zhang, Yinyin Qin, Tianfei Ran, Min Wang, Li Pei, Jun Pan   +9 more
doaj   +1 more source

Preeclampsia and Extracellular Vesicles [PDF]

Current Hypertension Reports, 2016
Preeclampsia is a hypertensive pregnancy disorder characterized by development of hypertension and proteinuria after 20 weeks of gestation that remains a leading cause of maternal and neonatal morbidity and mortality. While preeclampsia is believed to result from complex interactions between maternal and placental factors, the proximate pathophysiology
Gilani, Sarwat I., Weissgerber, Tracey L., Garovic, Vesna D., Jayachandran, Muthuvel   +3 more
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PD-L1 antibodies-armed exosomal vaccine for enhanced cancer immunotherapy by simultaneously in situ activating T cells and blocking PD-1/PD-L1 axis

Extracellular Vesicle, 2022
Tumor immunotherapy significantly rewards antigen-specific T-cell responses, which have been recognized as the foundation of adaptive immune responses.
Xinyue Dai, Zhaoshuo Wang, Miao Fan, Huifang Liu, Xinjian Yang, Xueyi Wang, Xiaohan Zhou, Yunlu Dai, Jinchao Zhang, Zhenhua Li   +9 more
doaj   +1 more source

Complex RNA world in small extracellular vesicles for liquid biopsy in cancer management

Extracellular Vesicle, 2022
Liquid biopsy is a valuable tool in oncology with its advantages of non-invasiveness, longitudinal sampling, and capturing the intra- and inter-tumor heterogeneity. Small extracellular vesicles (sEVs) are released by cells into various biological fluids,
Shuhong Wang, Yusheng Lin, Yishi Zhang, Xiaofu Qiu, Yunlong Pan, Sai-Ching Jim Yeung, Hao Zhang   +6 more
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Sucrose-based cryoprotective storage of extracellular vesicles

Extracellular Vesicle, 2022
Advancements in extracellular vesicle (EV) studies necessitate the development of optimized storage conditions to ensure preservation of physical and biochemical characteristics.
Sierra A. Walker, Irina Davidovich, Yubo Yang, Andrew Lai, Jenifer Pendiuk Goncalves, Vatsal Deliwala, Sara Busatto, Shane Shapiro, Na’ama Koifman, Carlos Salomon, Yeshayahu Talmon, Joy Wolfram   +11 more
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Single Extracellular VEsicle Nanoscopy

Journal of Extracellular Vesicles, 2023
AbstractExtracellular vesicles (EVs) and their cargo constitute novel biomarkers. EV subpopulations have been defined not only by abundant tetraspanins (e.g., CD9, CD63 and CD81) but also by specific markers derived from their source cells. However, it remains a challenge to robustly isolate and characterize EV subpopulations.
Andras Saftics, Sarah Abuelreich, Eugenia Romano, Ima Ghaeli, Nan Jiang, Michail Spanos, Kathleen M. Lennon, Gagandeep Singh, Saumya Das, Kendall Van Keuren‐Jensen, Tijana Jovanovic‐Talisman   +10 more
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Extracellular Vesicles in Transplantation [PDF]

Frontiers in Immunology, 2022
Extracellular vesicles (EVs) have been extensively studied in the last two decades. It is now well documented that they can actively participate in the activation or regulation of immune system functions through different mechanisms, the most studied of which include protein–protein interactions and miRNA transfers.
Nicolas Sailliet, Matti Ullah, Amandine Dupuy, Amanda K. A. Silva, Florence Gazeau, Hoa Le Mai, Sophie Brouard, Sophie Brouard   +7 more
openaire   +5 more sources