Results 131 to 140 of about 1,214,978 (300)

Extracellular vesicles as biomarkers for endometrial cancer – A systematic review

Translational Oncology
Background: The current method for diagnosing endometrial cancer and monitoring treatment response is invasive and fraught with both interobserver and intraobserver variability. Less invasive and more reproducible methods are desirable.
Eva Baxter, Soumyalekshmi Nair, Zoe West, Carlos Salomon, Andreas Obermair   +4 more
doaj   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

The role of glycogen synthase kinase 3 beta in the biogenesis of extracellular vesicles by modulating microtubule

, 2019
1
BAE, SEOYOON, GHO, YONG SONG
core  

Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells

, 2019
Mutations in β-catenin, especially at the residues critical for its degradation, render it constitutively active. Here, we show that mutant β-catenin can be transported via extracellular vesicles (EVs) and activate Wnt signalling pathway in the recipient
Liem, M, Fonseka, P, Samuel, M,, Gangoda, L, Keerthikumar, S, Collins, C, Kalra, H, Boukouris, S, Al, Saffar H, Chitti, SV   +9 more
core   +1 more source

Comprehensive strategy for identifying extracellular vesicle surface proteins as biomarkers for chronic kidney disease

Frontiers in Physiology
Chronic kidney disease (CKD) poses a significant health burden worldwide. Especially, obesity-induced chronic kidney disease (OCKD) is associated with a lack of accuracy in disease diagnostic methods.
Nahuel Aquiles Garcia, Hernan Gonzalez-King, Maiken Mellergaard, Maiken Mellergaard, Soumyalekshmi Nair, Carlos Salomon, Aase Handberg, Aase Handberg   +7 more
doaj   +1 more source

Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids

Advanced Healthcare Materials, EarlyView.
Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López, Jose I. Garcia‐Peiro, Felipe Hornos, Jose L. Hueso, Jesus Santamaria, J. Manuel Garcia‐Aznar   +5 more
wiley   +1 more source

Comparative studies on in vitro and in vivo inflammatory activities of extracellular vesicles and soluble factors derived

, 2019
1
김상수, GHO, YONG SONG
core  

Quantitative Analysis of Complement Membrane Attack Complex Proteins Associated with Extracellular Vesicles

Extracellular vesicles (EVs) represent a universal mechanism of intercellular communication in normal and pathological conditions. There are reports showing the presence of complement proteins in EV preparations, specifically those that can form a ...
Illarion V. Turko
core   +1 more source

Placenta‐derived extracellular vesicles: Signal messengers shuttling across the maternal‐fetal barrier

Interdisciplinary Medicine
Intercellular communication across the maternal‐fetal barrier is essential for maintaining physiological balance during pregnancy. As the structural foundation of the maternal‐fetal barrier, the placenta is the core site for material exchange and ...
Jiale Du, Maliang Tao, Yanxuan Xiao, Zhijian Wang, Bo Situ, Lei Zheng   +5 more
doaj   +1 more source