1α,25(OH)2D3 is an autocrine regulator of extracellular matrix turnover and growth factor release via ERp60 activated matrix vesicle metalloproteinases [PDF]
, 2007 Barbara D. Boyan +3 more
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Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
Advanced Biology, EarlyView.This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim +3 more
wiley +1 more source
HeliyonOvarian cancer is the most common gynaecological malignancy and the seventh most diagnosed cancer in females worldwide. Currently, it is the sixth leading cause of cancer related mortality among patients globally.
Nihar Godbole +15 more
doaj
Neurons produce FGF2 and VEGF and secrete them at least in part by shedding extracellular vesicles [PDF]
, 2007 Gabriella Schiera +5 more
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Extracellular vesicles as a next-generation drug delivery platform
Nature Nanotechnology, 2021 I. Herrmann, M. J. Wood, G. Fuhrmann
semanticscholar +1 more source
Advanced Biology, EarlyView.Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang +6 more
wiley +1 more source
Advanced Biology, EarlyView.The successful in situ polymerization of microtubules in giant polymer‐lipid hybrid vesicles is illustrated. The microtubules formed in the giant hybrid vesicles exhibit different morphologies including lumenal network formation and membrane association. Abstract Creating artificial cells with a dynamic cytoskeleton, akin to those in living cells, is a
Paula De Dios Andres +4 more
wiley +1 more source
Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: A form of communication during injury, infection, and cell damage [PDF]
, 2010 Antonio De Maio
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Extracellular vesicles are key intercellular mediators in the development of immune dysfunction to allergens in the airways [PDF]
, 2010 Tae Seop Shin +6 more
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Immunogenicity of Extracellular Vesicles
Advanced MaterialsAbstractExtracellular vesicles (EVs) are promising next‐generation therapeutics and drug delivery systems due to demonstrated safety and efficacy in preclinical models and early‐stage clinical trials. There is an urgent need to address the immunogenicity of EVs (beyond the apparent lack of immunotoxicity) to advance clinical development.
Yutian Xia +3 more
openaire +2 more sources