Results 71 to 80 of about 1,654,064 (188)

Control of breathing using an extracorporeal membrane lung

open access: yes, 1977
Various amounts of carbon dioxide were removed through an extracorporeal membrane lung in spontaneously breathing lambs. The decrease in alveolar ventilation was proportional to the fraction of total carbon dioxide removed by the membrane lung.
T. Kolobow   +3 more
core   +1 more source

Feasibility and safety of low-flow extracorporeal CO2 removal managed with a renal replacement platform to enhance lung-protective ventilation of patients with mild-to-moderate ARDS

open access: yesCritical Care, 2018
Background Extracorporeal carbon-dioxide removal (ECCO2R) might allow ultraprotective mechanical ventilation with lower tidal volume (VT) (
Matthieu Schmidt   +5 more
doaj   +1 more source

Quantifying the effects of hemoglobin saturation on plasma strong ion difference during blood oxygenation and decarboxylation

open access: yesPhysiological Reports, Volume 14, Issue 19, October 2026.
Abstract The strong ion difference (SID) is assessed to interpret acid–base disorders, yet measured plasma values are influenced by electrolyte redistribution across compartments. Current models focus on pH‐dependent plasma‐erythrocyte shifts. Here, we aim to quantify the effects of hemoglobin oxygen saturation (sO2).
Lorenzo Giosa   +11 more
wiley   +1 more source

Extracorporeal carbon dioxide removal

open access: yes, 1988
Using an animal model of acute respiratory failure (ARF), we evaluated two treatments: conventional mechanical pulmonary ventilation (MV) and continuous positive airway pressure (CPAP) with extracorporeal removal of CO2 by an artificial membrane lung. We
A. Riboni   +9 more
core   +1 more source

Physiological Basis of Extracorporeal Membrane Oxygenation and Extracorporeal Carbon Dioxide Removal in Respiratory Failure

open access: yes, 2021
Extracorporeal life support (ECLS) for severe respiratory failure has seen an exponential growth in recent years. Extracorporeal membrane oxygenation (ECMO) and extracorporeal CO2 removal (ECCO2R) represent two modalities that can provide full or partial
Lamas, Tomas   +17 more
core   +1 more source

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

open access: yesAdvanced Science, Volume 13, Issue 53, 24 September 2026.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba   +25 more
wiley   +1 more source

Interstitial pneumonia with autoimmune features: an additional risk factor for ARDS?

open access: yesAnnals of Intensive Care, 2017
Background Interstitial pneumonia with autoimmune features (IPAF) identifies a recently recognized autoimmune syndrome characterized by interstitial lung disease and autoantibodies positivity, but absence of a specific connective tissue disease diagnosis
Giacomo Grasselli   +8 more
doaj   +1 more source

Self‐Organized Vascularized Human Liver Spheroids: Serum‐Free Culture Conditions and Use as Tissue Building Blocks

open access: yesSmall, Volume 22, Issue 49, 1 September 2026.
This approach addresses a major challenge in tissue engineering: creating larger, vascularized tissues. Microvascular networks in liver spheroids are developed through self‐organization mediated by mesenchymal stem cells. These spheroids are maintained in serum‐reduced or serum‐free medium and serve as building blocks to form planar tissue layers ...
Alina Filatova   +10 more
wiley   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, Volume 13, Issue 43, 3 August 2026.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Treatment of renal stones by extracorporeal shockwave lithotripsy - An update [PDF]

open access: yes, 2001
Aim: Despite the extensive experience with minimal invasive stone therapy, there are still different views on the ideal management of renal stones. Materials and Methods: Analysis of the literature includes more than 14,000 patients.
Renner, Christian   +3 more
core   +1 more source

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