Neurobiology of Disease, 2013 Excitotoxicity plays a central role in the neuronal damage during ischemic stroke. Although growing evidence suggests that activation of extrasynaptic NMDA receptors initiates neuronal death, no direct evidence demonstrated their activation during ...
Qi-ping Dong, Jing-quan He, Zhen Chai
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Extrasynaptic NMDA Receptors Bidirectionally Modulate Intrinsic Excitability of Inhibitory Neurons [PDF]
, 2022 Lulu Yao +11 more
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Extrasynaptic α5GABAA receptors on proprioceptive afferents produce a tonic depolarization that modulates sodium channel function in the rat spinal cord [PDF]
, 2018 Ana M. Lucas‐Osma +7 more
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Modulating anxiety with extrasynaptic inhibition
, 2014 Traumatic experiences and stress can lead to complex behavioral adaptations, including increased levels of anxiety and fear generalization. The neuronal mechanisms underlying such maladaptive behavioral changes are, however, poorly understood. Numerous studies have indicated that, in both animals and humans, the amygdala is a key brain structure ...
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Extrasynaptic δGABAA receptors mediate resistance to migraine-like phenotype in rats
The Journal of Headache and PainBackground GABA, a key inhibitory neurotransmitter, has synaptic and extrasynaptic receptors on the postsynaptic neuron. Background GABA, which spills over from the synaptic cleft, acts on extrasynaptic delta subunit containing GABAA receptors.
Berkay Alpay +5 more
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Backpropagating Action Potentials Enable Detection of Extrasynaptic Glutamate by NMDA Receptors [PDF]
, 2012 Yu‐Wei Wu +4 more
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, 2012 The simulation data presented here, and the conceptual framework developed for their interpretation are, both, in need of substantial refinement and extension.
Werner, prof. Gerhard
core
Increased Exon 5 Expression Alters Extrasynaptic NMDA Receptors in Cerebellar Neurons [PDF]
, 2000 Kate Prybylowski +3 more
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Glial Expression of the Caenorhabditis elegans Gene swip-10 Supports Glutamate Dependent Control of Extrasynaptic Dopamine Signaling [PDF]
, 2015 J. Andrew Hardaway +11 more
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N-Methyl-d-aspartate (NMDA) Receptor NR2 Subunit Selectivity of a Series of Novel Piperazine-2,3-dicarboxylate Derivatives: Preferential Blockade of Extrasynaptic NMDA Receptors in the Rat Hippocampal CA3-CA1 Synapse [PDF]
, 2009 Blaise M. Costa +8 more
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