Results 111 to 120 of about 22,128 (213)
Frontiers in Physiology, 2012 Persistent peripheral inflammation changes AMPA receptor (AMPAR) trafficking in dorsal horn neurons by promoting internalization of GluR2-containing, Ca2+-impermeable AMPARs from the synapses and by increasing insertion of GluR1-containing, Ca2 ...
Olga eKopach +3 more
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Frontiers in Physiology, 2012 Communication between neurons is achieved by rapid signal transduction via highly specialized structural elements known as synaptic contacts. In addition, numerous extrasynaptic mechanisms provide a flexible platform for the local regulation of synaptic ...
Olivier eCamiré +2 more
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Pharmacological characterisation of murine α4β1δ GABAA receptors expressed in Xenopus oocytes [PDF]
, 2015 BACKGROUND: GABAA receptor subunit composition has a profound effect on the receptor's physiological and pharmacological properties. The receptor β subunit is widely recognised for its importance in receptor assembly, trafficking and post-translational ...
Smart, TG, Villumsen, IS, Wellendorph, P
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The activity of isolated neurons and the modulatory state of an isolated nervous system represent a recent behavioural state [PDF]
, 2015 Behavioural/motivational state is known to influence nearly all aspects of physiology and behaviour. The cellular basis of behavioural state control is only partially understood.
Chistopolsky, Ilya A. +4 more
core +1 more source
, 2016 NMDA receptors are ion channels activated by the neurotransmitter glutamate in the mammalian brain and are important in synaptic function and plasticity, but are also found in extrasynaptic locations and influence neuronal excitability.
Scheppach, Christian
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Frontiers in Physiology, 2012 Repetitive synaptic stimulation overcomes the ability of astrocytic processes to clear glutamate from the extracellular space, allowing some dendritic segments to become submerged in a pool of glutamate.
Katerina D Oikonomou +3 more
doaj +1 more source
Crosstalk Between Brain-Derived Neurotrophic Factor And N-Methyl-D-Aspartate Receptor Signaling In Neurons [PDF]
, 2008 Glutamate is the major excitatory neurotransmitter in brain exerting prosurvival effect on neurons via N-methyl-D-aspartate receptor (NMDAR) signaling under physiological conditions.
Georgiev, Danko +3 more
core
Extrasynaptic distribution of monoamine transporters and receptors
, 2000 Publisher Summary Extra-synaptic, as well as synaptic sites for monoaminergic transmission have been elucidated by using electron microscopic immunocytochemistry for the localization of sequence specific antipeptide antisera against recently cloned vesicular and plasmalemmal monoamine transporters and receptors.
openaire +2 more sources
NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content
Cell Reports, 2019 Summary: In mature neurons, postsynaptic N-methyl-D-aspartate receptors (NMDARs) are segregated into two populations, synaptic and extrasynaptic, which differ in localization, function, and associated intracellular cascades. These two pools are connected
Andrew M. Chiu +6 more
doaj +1 more source
Extrasynaptic Release of GABA by Retinal Dopaminergic Neurons
Journal of Neurophysiology, 2009 GABA release by dopaminergic amacrine (DA) cells of the mouse retina was detected by measuring Cl−currents generated by isolated perikarya in response to their own neurotransmitter. The possibility that the Cl−currents were caused by GABA release from synaptic endings that had survived the dissociation of the retina was ruled out by examining confocal ...
Hajime, Hirasawa +2 more
openaire +3 more sources