Results 111 to 120 of about 14,388 (200)

Extrasynaptic receptors on cell bodies of neurons in central nervous system of the leech

, 1977
1. A systematic study has been made of the sensitivity of identified sensory and motoneurons in the leech central nervous system to chemical transmitter substances. 2.
P. B. Sargent, J. G. Nicholls, K. W. Yau
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GABAAR isoform and subunit structural motifs determine synaptic and extrasynaptic receptor localisation [PDF]

, 2020
GABAA receptors (GABAARs) are the principal inhibitory neurotransmitter receptors in the central nervous system. They control neuronal excitability by synaptic and tonic forms of inhibition mostly mediated by different receptor subtypes located in ...
Hannan, S, Izquierdo, P, Thomas, P, Tench, B, Smart, TG, Minere, M, Harris, J   +6 more
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Therapeutic targeting of the pathological triad of extrasynaptic NMDA receptor signaling in neurodegenerations

, 2017
Activation of extrasynaptic N-methyl-d-aspartate (NMDA) receptors causes neurodegeneration and cell death. The disease mechanism involves a pathological triad consisting of mitochondrial dysfunction, loss of integrity of neuronal structures and ...
Hilmar Bading
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Factors Influencing Short-term Synaptic Plasticity in the Avian Cochlear Nucleus Magnocellularis

Journal of Experimental Neuroscience, 2015
Defined as reduced neural responses during high rates of activity, synaptic depression is a form of short-term plasticity important for the temporal filtering of sound.
Jason Tait Sanchez Quinones, Quinones Karla, Otto-Meyer Sebastian   +2 more
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Connectomics of extrasynaptic signalling: applications to the nervous system of Caenorhabditis elegans

, 2017
Connectomics – the study of neural connectivity – is primarily concerned with the mapping and characterisation of wired synaptic links; however, it is well established that long-distance chemical signalling via extrasynaptic volume transmission is also ...

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contribution des récepteurs NMDA extrasynatiques à l'activité en bouffée dans les neurones dopaminergiques de la substance noire compacte

Movement initiation is preceded by bursting activity and increased dopamine release by substantia nigra pars compacta neurons. The participation of NMDARs is essential to the generation of bursts but the mechanisms regulating their level of activation ...
Engel, Dominique
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NMDARs in Alzheimer’s Disease: Between Synaptic and Extrasynaptic Membranes

N-methyl-D-aspartate receptors (NMDARs) are glutamate receptors with key roles in synaptic communication and plasticity. The activation of synaptic NMDARs initiates plasticity and stimulates cell survival.
Cuchillo-Ibáñez, Inmaculada, Sergio Escamilla, Sáez-Valero, Javier, Javier Sáez-Valero, Inmaculada Cuchillo-Ibáñez, Escamilla, Sergio   +5 more
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Nuclear Jacob immunoreactivity at different culture ages following synaptic or extrasynaptic NMDA receptor activation.

, 2013
A1–A3 and C1–C3) Representative fluorescence images for anti-Jacob and DAPI stained hippocampal primary neurons at 9, 16 and 23 DIV. Cultures were stimulated with protocols activating synaptic (bicuculline, 4-AP) and extrasynaptic NMDA receptors ...
Jin Yu (53103), Thomas Behnisch (355864), Anna Karpova (80098), Ying Chen (9697), Philipp Bethge (355866), PingAn YuanXiang (355865), Michael R. Kreutz (194048), Marina Mikhaylova (80099), Suhel Parvez (269139), Julietta U. Frey (355867)   +9 more
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Encoding and Transducing the Synaptic or Extrasynaptic Origin of NMDA Receptor Signals to the Nucleus

, 2013
SummaryThe activation of N-methyl-D-aspartate-receptors (NMDARs) in synapses provides plasticity and cell survival signals, whereas NMDARs residing in the neuronal membrane outside synapses trigger neurodegeneration.
Bethge, Philipp, Naumann, Michael, Gundelfinger, Eckart D., Rankovic, Vladan, Sahin, Jale, Bär, Julia, Karpova, Anna, Behnisch, Thomas, Spilker, Christina, Kähne, Thilo, Kreutz, Michael R., Reddy, Pasham Parameshwar, Kaushik, Rahul, Zuschratter, Werner, Bera, Sujoy, Mikhaylova, Marina   +15 more
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Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

, 2010
SummaryN-methyl-D-aspartate receptor (NMDAR) excitotoxicity is implicated in the pathogenesis of Huntington's disease (HD), a late-onset neurodegenerative disorder.
Pouladi, Mahmoud A., Ko, Rebecca W.Y., Hayden, Michael R., Boyd, Jamie D., Hines, Rochelle M., Graham, Rona K., Raymond, Lynn A., Milnerwood, Austen J., Gladding, Clare M., Kaufman, Alexandra M., Murphy, Timothy H., Vasuta, Oana C.   +11 more
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