Results 101 to 110 of about 14,388 (200)
Photo-antagonism of the GABAA receptor [PDF]
, 2014 Neurotransmitter receptor trafficking is fundamentally important for synaptic transmission and neural network activity. GABAA receptors and inhibitory synapses are vital components of brain function, yet much of our knowledge regarding receptor mobility ...
Topf, Maya +15 more
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Frontiers in Physiology, 2012 Communication between neurons is achieved by rapid signal transduction via highly specialized structural elements known as synaptic contacts. In addition, numerous extrasynaptic mechanisms provide a flexible platform for the local regulation of synaptic ...
Olivier eCamiré +2 more
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Extrasynaptic distribution of monoamine transporters and receptors
, 2000 Publisher Summary Extra-synaptic, as well as synaptic sites for monoaminergic transmission have been elucidated by using electron microscopic immunocytochemistry for the localization of sequence specific antipeptide antisera against recently cloned vesicular and plasmalemmal monoamine transporters and receptors.
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Extrasynaptic GABAA Receptors: Their Function in the CNS and Implications for Disease
, 2012 Over the past two decades, research has identified extrasynaptic GABAA receptor populations that enable neurons to sense the low ambient GABA concentrations present in the extracellular space in order to generate a form of tonic inhibition not previously
Brickley, Stephen G., Mody, Istvan
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Frontiers in Physiology, 2012 Repetitive synaptic stimulation overcomes the ability of astrocytic processes to clear glutamate from the extracellular space, allowing some dendritic segments to become submerged in a pool of glutamate.
Katerina D Oikonomou +3 more
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, 2011 We characterized the distribution of AMPA receptor (AMPAR) subunits and the transmembrane AMPA receptor regulatory proteins (TARPs) γ-2 and γ-4 in adult rat nucleus accumbens (NAc) using a method that separates plasma membranes into synaptic membrane ...
Wolf, Marina +9 more
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NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content
Cell Reports, 2019 Summary: In mature neurons, postsynaptic N-methyl-D-aspartate receptors (NMDARs) are segregated into two populations, synaptic and extrasynaptic, which differ in localization, function, and associated intracellular cascades. These two pools are connected
Andrew M. Chiu +6 more
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Thalamic extrasynaptic GABAA receptors are required for typical absence seizures [PDF]
, 2009 Aberrant GABAergic inhibition in thalamo-cortical networks has been identified as a potential mechanism for spike-and-wave discharge (SWD) generation. Thalamocortical (TC) neurons in the ventrobasal (VB) thalamus receive both ‘phasic’ and ‘tonic’ GABAA ...
Cope, David W. +5 more
core
Sharing vesicles between central presynaptic terminals: implications for synaptic function
Frontiers in Synaptic Neuroscience, 2010 Presynaptic terminals in hippocampal neurons house functionally distinct vesicle pools, the size, structure and biochemical features of which are major determinants of presynaptic strength and performance.
Kevin Staras, Tiago Branco, Tiago Branco
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Extrasynaptic Release of GABA by Retinal Dopaminergic Neurons
Journal of Neurophysiology, 2009 GABA release by dopaminergic amacrine (DA) cells of the mouse retina was detected by measuring Cl−currents generated by isolated perikarya in response to their own neurotransmitter. The possibility that the Cl−currents were caused by GABA release from synaptic endings that had survived the dissociation of the retina was ruled out by examining confocal ...
Hajime, Hirasawa +2 more
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