Results 81 to 90 of about 15,145 (185)
Frontiers in Physiology, 2012 Persistent peripheral inflammation changes AMPA receptor (AMPAR) trafficking in dorsal horn neurons by promoting internalization of GluR2-containing, Ca2+-impermeable AMPARs from the synapses and by increasing insertion of GluR1-containing, Ca2 ...
Olga eKopach +3 more
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Extrasynaptic distribution of monoamine transporters and receptors
, 2000 Publisher Summary Extra-synaptic, as well as synaptic sites for monoaminergic transmission have been elucidated by using electron microscopic immunocytochemistry for the localization of sequence specific antipeptide antisera against recently cloned vesicular and plasmalemmal monoamine transporters and receptors.
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Frontiers in Physiology, 2012 Communication between neurons is achieved by rapid signal transduction via highly specialized structural elements known as synaptic contacts. In addition, numerous extrasynaptic mechanisms provide a flexible platform for the local regulation of synaptic ...
Olivier eCamiré +2 more
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Frontiers in Physiology, 2012 Repetitive synaptic stimulation overcomes the ability of astrocytic processes to clear glutamate from the extracellular space, allowing some dendritic segments to become submerged in a pool of glutamate.
Katerina D Oikonomou +3 more
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NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content
Cell Reports, 2019 Summary: In mature neurons, postsynaptic N-methyl-D-aspartate receptors (NMDARs) are segregated into two populations, synaptic and extrasynaptic, which differ in localization, function, and associated intracellular cascades. These two pools are connected
Andrew M. Chiu +6 more
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Connectomics of extrasynaptic signalling: applications to the nervous system of Caenorhabditis elegans [PDF]
, 2017 Connectomics – the study of neural connectivity – is primarily concerned with the mapping and characterisation of wired synaptic links; however, it is well established that long-distance chemical signalling via extrasynaptic volume transmission is also ...
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Extrasynaptic GABAA receptors in the crosshairs of hormones and ethanol [PDF]
Neurochemistry International, 2008 Gamma-aminobutyric acid (GABA) is the main chemical inhibitory neurotransmitter in the brain. In the central nervous system (CNS) it acts on two distinct types of receptor: an ion channel, i.e., an "ionotropic" receptor permeable to Cl- and HCO3- (GABAA receptors) and a G-protein coupled "metabotropic" receptor that is linked to various effector ...
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Extrasynaptic Release of GABA by Retinal Dopaminergic Neurons
Journal of Neurophysiology, 2009 GABA release by dopaminergic amacrine (DA) cells of the mouse retina was detected by measuring Cl−currents generated by isolated perikarya in response to their own neurotransmitter. The possibility that the Cl−currents were caused by GABA release from synaptic endings that had survived the dissociation of the retina was ruled out by examining confocal ...
Hajime, Hirasawa +2 more
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GABAAR isoform and subunit structural motifs determine synaptic and extrasynaptic receptor localisation [PDF]
, 2020 GABAA receptors (GABAARs) are the principal inhibitory neurotransmitter receptors in the central nervous system. They control neuronal excitability by synaptic and tonic forms of inhibition mostly mediated by different receptor subtypes located in ...
Hannan, S +6 more
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Sharing vesicles between central presynaptic terminals: implications for synaptic function
Frontiers in Synaptic Neuroscience, 2010 Presynaptic terminals in hippocampal neurons house functionally distinct vesicle pools, the size, structure and biochemical features of which are major determinants of presynaptic strength and performance.
Kevin Staras, Tiago Branco, Tiago Branco
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