Results 141 to 150 of about 26,166 (275)

Acetylcholine receptors in regenerating muscle accumulate at original synaptic sites in the absence of the nerve. [PDF]

, 1979
We examined the role of nerve terminals in organizing acetylcholine receptors on regenerating skeletal-muscle fibers. When muscle fibers are damaged, they degenerate and are phagocytized, but their basal lamina sheaths survive.
Burden, SJ, McMahan, UJ, Sargent, PB
core  

Common Ribs of Inhibitory Synaptic Dysfunction in the Umbrella of Neurodevelopmental Disorders

, 2018
The term neurodevelopmental disorder (NDD) is an umbrella term used to group together a heterogeneous class of disorders characterized by disruption in cognition, emotion, and behavior, early in the developmental timescale.
Hines, Rochelle M., Joya, Christina, Rodriguez, Rachel Ali   +2 more
core   +2 more sources

Ketamine: NMDA receptors and beyond [PDF]

, 2016
Human studies examining the effects of the dissociative anesthetic ketamine as a model for psychosis and as a rapidly acting antidepressant have spurred great interest in understanding ketamine's actions at molecular, cellular, and network levels ...
Izumi, Yukitoshi, Mennerick, Steven, Zorumski, Charles F   +2 more
core   +2 more sources

Extrasynaptic glutamate receptor activation as cellular bases for dynamic range compression in pyramidal neurons

Frontiers in Physiology, 2012
Repetitive synaptic stimulation overcomes the ability of astrocytic processes to clear glutamate from the extracellular space, allowing some dendritic segments to become submerged in a pool of glutamate.
Katerina D Oikonomou, Shaina M Short, Matthew T Rich, Srdjan D Antic   +3 more
doaj   +1 more source

Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury

Neuron, 2022
Pengyu Zong, Jianlin Feng, Zhichao Yue, Yunfeng Li, Gongxiong Wu, Baonan Sun, Yanlin He, Barbara Miller, Albert S. Yu, Zhongping Su, Jia Xie, Y. Mori, Bing Hao, Lixia Yue   +13 more
semanticscholar   +1 more source

Extrasynaptic NMDA Receptors Bidirectionally Modulate Intrinsic Excitability of Inhibitory Neurons [PDF]

, 2022
Lulu Yao, Yi Rong, Xiaoyan Ma, Haifu Li, Di Deng, Yongjun Chen, Sungchil Yang, Tao Peng, Tao Ye, Feixue Liang, Nenggui Xu, Qiang Zhou   +11 more
openalex   +1 more source

Extrasynaptic distribution of monoamine transporters and receptors

, 2000
Publisher Summary Extra-synaptic, as well as synaptic sites for monoaminergic transmission have been elucidated by using electron microscopic immunocytochemistry for the localization of sequence specific antipeptide antisera against recently cloned vesicular and plasmalemmal monoamine transporters and receptors.
openaire   +2 more sources

Astrocytic Ca2+ waves mediate activation of extrasynaptic NMDA receptors in hippocampal neurons to aggravate brain damage during ischemia

Neurobiology of Disease, 2013
Excitotoxicity plays a central role in the neuronal damage during ischemic stroke. Although growing evidence suggests that activation of extrasynaptic NMDA receptors initiates neuronal death, no direct evidence demonstrated their activation during ...
Qi-ping Dong, Jing-quan He, Zhen Chai
doaj   +1 more source

Involvement of the GluN2A and GluN2B Subunits in Synaptic and Extrasynaptic N-methyl-d-aspartate Receptor Function and Neuronal Excitotoxicity [PDF]

, 2013
Xianju Zhou, Qi Ding, Zhuoyou Chen, Huifang Yun, Hongbing Wang   +4 more
openalex   +1 more source

Extrasynaptic Release of GABA by Retinal Dopaminergic Neurons

Journal of Neurophysiology, 2009
GABA release by dopaminergic amacrine (DA) cells of the mouse retina was detected by measuring Cl−currents generated by isolated perikarya in response to their own neurotransmitter. The possibility that the Cl−currents were caused by GABA release from synaptic endings that had survived the dissociation of the retina was ruled out by examining confocal ...
Hajime, Hirasawa, Michelino, Puopolo, Elio, Raviola   +2 more
openaire   +3 more sources