Results 151 to 160 of about 26,166 (275)

Sharing vesicles between central presynaptic terminals: implications for synaptic function

Frontiers in Synaptic Neuroscience, 2010
Presynaptic terminals in hippocampal neurons house functionally distinct vesicle pools, the size, structure and biochemical features of which are major determinants of presynaptic strength and performance.
Kevin Staras, Tiago Branco, Tiago Branco
doaj   +1 more source

Extrasynaptic GABAA receptors in mediodorsal thalamic nucleus modulate fear extinction learning [PDF]

, 2014
Afshin Paydar, Boyoung Lee, Gireesh Gangadharan, Sukchan Lee, Eun Mi Hwang, Hee‐Sup Shin   +5 more
openalex   +1 more source

Fingolimod Limits Acute Aβ Neurotoxicity and Promotes Synaptic Versus Extrasynaptic NMDA Receptor Functionality in Hippocampal Neurons

Scientific Reports, 2017
Fingolimod, also known as FTY720, is an analogue of the sphingolipid sphingosine, which has been proved to be neuroprotective in rodent models of Alzheimer’s disease (AD).
P. Joshi, M. Gabrielli, L. Ponzoni, S. Pelucchi, M. Stravalaci, M. Beeg, S. Mazzitelli, D. Braida, M. Sala, E. Boda, A. Buffo, M. Gobbi, F. Gardoni, M. Matteoli, E. Marcello, C. Verderio   +15 more
semanticscholar   +1 more source

Extrasynaptic signaling enables an asymmetric juvenile motor circuit to produce symmetric undulation

, 2022
Yangning Lu, Tosif Ahamed, Ben Mulcahy, Jun Meng, Daniel Witvliet, Sihui Asuka Guan, Douglas Holmyard, Wesley Hung, Quan Wen, Andrew Chisholm, Aravinthan D. T. Samuel, Mei Zhen   +11 more
openalex   +2 more sources

Imbalanced post- and extrasynaptic SHANK2A functions during development affect social behavior in SHANK2-mediated neuropsychiatric disorders [PDF]

, 2021
Ahmed Eltokhi, Miguel A. Gonzalez‐Lozano, Lars‐Lennart Oettl, Andrei Rozov, Claudia Pitzer, Ralph Röth, Simone Berkel, Markus Hüser, Aliona Harten, Wolfgang Kelsch, August B. Smit, Gudrun Rappold, Rolf Sprengel   +12 more
openalex   +1 more source

Single Ethanol Withdrawal Regulates Extrasynaptic δ-GABAA Receptors Via PKCδ Activation

Frontiers in Molecular Neuroscience, 2018
Alcohol (ethanol, EtOH) is one of the most widely abused drugs with profound effects on brain function and behavior. GABAA receptors (GABAARs) are one of the major targets for EtOH in the brain.
Juan Chen, Yang He, Yan Wu, Hang Zhou, Li-Da Su, Wei-Nan Li, Richard W. Olsen, Jing Liang, Yu-Dong Zhou, Yi Shen   +9 more
doaj   +1 more source

Meta-Potentiation: Neuro-Astroglial Interactions Supporting Perceptual Consciousness [PDF]

, 2007
Conscious perceptual processing involves the sequential activation of cortical networks at several brain locations, and the onset of oscillatory synchrony affecting the same neuronal population.
Alfredo Pereira Jr, Fá
core   +2 more sources

Distinct Roles for μ-Calpain and m-Calpain in Synaptic NMDAR-Mediated Neuroprotection and Extrasynaptic NMDAR-Mediated Neurodegeneration [PDF]

, 2013
Yubin Wang, Víctor Briz, Athar H. Chishti, Xiaoning Bi, Michel Baudry   +4 more
openalex   +1 more source

Rapid homeostatic downregulation of LTP by extrasynaptic GluN2B receptors

Journal of Neurophysiology, 2018
Although the activation of extrasynaptic GluN2B-containing N-methyl-d-aspartate (NMDA) receptors has been implicated in neurodegenerative diseases, such as Alzheimer’s and Huntington’s disease, their physiological function remains unknown. In this study,
Jary Y. Delgado, A. E. Fink, S. Grant, T. O’Dell, P. Opazo   +4 more
semanticscholar   +1 more source

Extrasynaptic δGABAA receptors mediate resistance to migraine-like phenotype in rats

The Journal of Headache and Pain
Background GABA, a key inhibitory neurotransmitter, has synaptic and extrasynaptic receptors on the postsynaptic neuron. Background GABA, which spills over from the synaptic cleft, acts on extrasynaptic delta subunit containing GABAA receptors.
Berkay Alpay, Bariscan Cimen, Elif Akaydin, Filiz Onat, Hayrunnisa Bolay, Yildirim Sara   +5 more
doaj   +1 more source