Modulating anxiety with extrasynaptic inhibition
Traumatic experiences and stress can lead to complex behavioral adaptations, including increased levels of anxiety and fear generalization. The neuronal mechanisms underlying such maladaptive behavioral changes are, however, poorly understood. Numerous studies have indicated that, in both animals and humans, the amygdala is a key brain structure ...
openaire +3 more sources
THIP, a Hypnotic and Antinociceptive Drug, Enhances an Extrasynaptic GABAA Receptor-mediated Conductance in Mouse Neocortex [PDF]
Kim Ryun Drasbek, Kimmo Jensen
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Factors Influencing Short-term Synaptic Plasticity in the Avian Cochlear Nucleus Magnocellularis
Defined as reduced neural responses during high rates of activity, synaptic depression is a form of short-term plasticity important for the temporal filtering of sound.
Jason Tait Sanchez Quinones +2 more
doaj +1 more source
N-Methyl-d-aspartate (NMDA) Receptor NR2 Subunit Selectivity of a Series of Novel Piperazine-2,3-dicarboxylate Derivatives: Preferential Blockade of Extrasynaptic NMDA Receptors in the Rat Hippocampal CA3-CA1 Synapse [PDF]
Blaise M. Costa +8 more
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The simulation data presented here, and the conceptual framework developed for their interpretation are, both, in need of substantial refinement and extension.
Werner, prof. Gerhard
core
The Predominance of Electric Transport in Synaptic Transmission [PDF]
The quantitative description of the motion of neurotransmitters in the synaptic cleft appears to be one of the most difficult problems in the modeling of synapses.
Hamid Reza Noori
core +1 more source
Postnatal Switch from Synaptic to Extrasynaptic Transmission between Interneurons and NG2 Cells [PDF]
Mateo Vélez‐Fort +4 more
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Single-Channel Properties of Synaptic and Extrasynaptic GABAAReceptors Suggest Differential Targeting of Receptor Subtypes [PDF]
Stephen G. Brickley +2 more
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Synaptic environment and extrasynaptic glutamate signals: The quest continues
D. Rusakov, M. Stewart
semanticscholar +1 more source

