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Neurosteroids and Extrasynaptic GABAA Receptors
2014Steroid sex hormones are generally thought to act through intracellular receptors, where they regulate gene expression and protein synthesis, an effect that takes minutes to hours to occur. However, steroid metabolites can also directly modulate the activity of numerous ligand-gated ion channels. These metabolites can be synthesised de novo in the CNS,
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Synaptic and Extrasynaptic Mitochondria
2022Vitória Girelli de Oliveira +3 more
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Extrasynaptic NMDA Receptors Reshape Gene Ranks
Science's STKE, 2007The N -methyl-D-aspartate (NMDA) subtype of glutamate receptors (NMDAR) plays a key role in the control of neuronal plasticity and cell survival by modifying the activity of different signaling pathways and numerous genes.
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Diffusional extrasynaptic neurotransmission via glutamate and GABA
Neuroscience and Behavioral Physiology, 2005Glutamate and GABA are the main synaptic neurotransmitters in the hippocampus. However, their actions are not limited only to the local postsynaptic zone. These amino acids can be released into the extrasynaptic space by glutamate and GABA reuptake, glial exocytosis, osmotic shock, and spillover (flowing out of the synaptic cleft).
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Extrasynaptic receptors and parasynaptic communication in the brain
Brain Research Bulletin, 1999openaire +2 more sources
Extrasynaptic AMPA receptors in the dorsal horn: Evidence and functional significance
Brain Research Bulletin, 2013Olga Kopach, Nana Voitenko
exaly
Dysregulation of synaptic and extrasynaptic N-methyl-D-aspartate receptors induced by amyloid-β
Neuroscience Bulletin, 2013Shao Li
exaly