Results 61 to 70 of about 70,107 (293)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Non-existence of stationary two-black-hole configurations: The degenerate case

, 2011
In a preceding paper we examined the question whether the spin-spin repulsion and the gravitational attraction of two aligned sub-extremal black holes can balance each other.
A. Tomimatsu, B. Carter, D. Kramer, D. Kramer, G. Neugebauer, G. Neugebauer, G. Neugebauer, G. Neugebauer, G. Neugebauer, G. Neugebauer, G. Weinstein, Gernot Neugebauer, I. Booth, I. Cabrera-Munguia, J. Hennig, Jörg Hennig, M. Ansorg, M. Yamazaki, P. Hájiček, P.T. Chruściel, R. Beig, R. Beig, R. Meinel, S. Alexakis, S. Alexakis, S.W. Hawking, V.S. Manko, Y.Y. Li, Y.Y. Li   +28 more
core   +1 more source

Solving 1D crossing and QFT2/CFT1

Journal of High Energy Physics
We provide an effective solution of the 1D crossing equation. We begin by arguing that crossing constraints can be recast in terms of bases of sum rules associated to special sets of CFT data — extremal solutions — which solve these constraints in a ...
Kausik Ghosh, Miguel F. Paulos, Noé Suchel   +2 more
doaj   +1 more source

Payne-Sperb-Stakgold Type Inequality for a Wedge-Like Membrane

International Journal of Analysis and Applications, 2022
For a bounded domain contained in a wedge, we give a new Payne-Sperb-Stakgold type inequality for the solution of a semi-linear equation. The result is isoperimetric in the sense that the sector is the unique extremal domain.
Abir Sboui, Abdelhalim Hasnaoui
doaj   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Extremal Solutions and Relaxation Problems for Fractional Differential Inclusions

Abstract and Applied Analysis, 2013
We present the existence of extremal solution and relaxation problem for fractional differential inclusion with initial conditions.
Juan J. Nieto, Abdelghani Ouahab, P. Prakash   +2 more
doaj   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

On the Rotating Charged Black String Solution

, 1993
A rotating charged black string solution in the low energy effective field theory describing five dimensional heterotic string theory is constructed. The solution is labelled by mass, electric charge, axion charge and angular momentum per unit length ...
A. Dabholkar, A. Giveon, A. Giveon, A. Kumar, A. Sen, A. Sen, A. Sen, A. Sen, A. Shapere, C. Callan, C. Callan, C. Nappi, D. Garfinkle, E. Witten, G. Gibbons, G. Gibbons, G. Gibbons, G. Horowitz, G. Horowitz, G. Mandal, G. Veneziano, J. Horne, J. Horne, J. Horne, J. Maharana, J. Maharana, J. Panvel, K. Meissner, M. Duff, M. Duff, M. Gasperini, M. Gasperini, M. Rocek, P. Horava, R. C. Myers, R. C. Myers, S. F. Hassan, S. F. Hassan, S. Giddings, S. Kar, S. Kar, S. Khastgir, S. Khastgir, S. Khastgir, Swapna Mahapatra, T. Busher, T. Busher, V. P. Frolov   +47 more
core   +2 more sources

Complement to thermodynamics of dyonic Taub-NUT-AdS spacetime

Journal of High Energy Physics, 2021
We examine the thermodynamics of Euclidean dyonic Taub-Nut/Bolt-AdS4 black holes for a variety of horizon geometries to understand how gauge field regularity conditions influence the thermodynamic relations.
Robert B. Mann, Leopoldo A. Pando Zayas, Miok Park   +2 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source