Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Existence and comparison results for quasilinear evolution hemivariational inequalities
We generalize the sub-supersolution method known for weak solutions of single and multivalued nonlinear parabolic problems to quasilinear evolution hemivariational inequalities.
Siegfried Carl +2 more
doaj
Particle acceleration near a rotating charged black hole in 4D Einstein-Gauss-Bonnet gravity
We investigate the horizon structure and ergosphere in a charged rotating black hole within 4D Einstein-Gauss-Bonnet gravity, which introduces additional parameters (Q) because of the charge and Gauss-Bonnet parameter (β), besides the mass (M) and ...
Abdurakhmon Nosirov +4 more
doaj +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Regularity of stable solutions to semilinear elliptic equations on Riemannian models
We consider the reaction-diffusion problem -Δgu = f(u) in ℬR with zero Dirichlet boundary condition, posed in a geodesic ball ℬR with radius R of a Riemannian model (M,g).
Castorina Daniele, Sanchón Manel
doaj +1 more source
Extremal solutions for measure differential inclusions via Stieltjes derivatives
Stieltjes derivatives represent a new unification of discrete and continuous calculus consisting in a differentiation process with respect to a given non-decreasing function g.
Giselle A. Monteiro, Bianca Satco
doaj +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
Black Hole in the Expanding Universe with Arbitrary Power-Law Expansion
We present a time-dependent and spatially inhomogeneous solution that interpolates the extremal Reissner-Nordstr\"om (RN) black hole and the Friedmann-Lema\^itre-Robertson-Walker (FLRW) universe with arbitrary power-law expansion. It is an exact solution
Maeda, Kei-ichi, Nozawa, Masato
core +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source

