Results 61 to 70 of about 2,095 (173)

Mitochondrial protein IF1 is a potential regulator of glucagon-like peptide (GLP-1) secretion function of the mouse intestine

Acta Pharmaceutica Sinica B, 2021
IF1 (ATPIF1) is a nuclear DNA-encoded mitochondrial protein whose activity is inhibition of the F1Fo-ATP synthase to control ATP production. IF1 activity remains unknown in the regulation of GLP-1 activity.
Ying Wang, Jiaojiao Zhang, Xinyu Cao, Yaya Guan, Shuang Shen, Genshen Zhong, Xiwen Xiong, Yanhong Xu, Xiaoying Zhang, Hui Wang, Jianping Ye   +10 more
doaj   +1 more source

Magnesium as a Bioenergetic Checkpoint Linking Mitochondrial Function, Metabolic Disease, and Aging

Aging Cell, Volume 25, Issue 6, June 2026.
This review positions magnesium as a central bioenergetic checkpoint that orchestrates mitochondrial function and metabolic resilience. By defining the functional ATP pool and stabilizing mitochondrial performance, magnesium homeostasis serves as a mechanistic link between renal handling, metabolic disease, and the aging process.
Chien‐Wei Huang, Chen‐Yueh Wen, Andy P. Tsai, Boyang Wang, Kuan‐Hao Tsui, Yu‐Juei Hsu, Chia‐Jung Li   +6 more
wiley   +1 more source

Heterogeneous metabolic response of endothelial cells from different vascular beds to experimental hyperglycaemia and metformin

The Journal of Physiology, Volume 604, Issue 11, Page 4208-4224, 1 June 2026.
Abstract figure legend Diabetes mellitus is associated with vascular pathology that leads to vascular complications in several tissues, such as retinopathy of the eye. Endothelial dysfunction plays a pivotal role in the progression of each complication.
C. McAleese, G. Joudah, I. P. Salt, J. R. Petrie, J. M. Leiper, Laura B. Dowsett   +5 more
wiley   +1 more source

Metalloids: Semi as Metals yet Full of Antimicrobial Potential

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm, Muhammad Jawad Nasim, Claus Jacob   +2 more
wiley   +1 more source

The ATP synthase of Streptomyces lividans: characterization and purification of the F1Fo complex

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1996
AbstractEverted membrane vesicles of the Gram-positive eubacterium Streptomyces lividans were prepared and the ATP synthase (F1Fo) was characterized in its membrane-bound form. In addition, the F1Fo complex was solubilized, purified, and functionally reconstituted into phospholipid vesicles.
Hensel, Michael, Achmus, Heike, Deckers-Hebestreit, Gabriele, Altendorf, Karlheinz   +3 more
openaire   +1 more source

Partial Reactions of the ATP Synthesis Reaction in the E. Coli βD380C Mutant F1Fo-ATP Synthase [PDF]

Biophysical Journal, 2010
The initial stage of ATP synthesis by the E. coli wild type (WT) and mutant βD380C F1Fo-ATPase was compared at saturating substrate concentrations and a proton-motive force (pmf) of ∼315 mV. The enzymes catalyze both ATP hydrolysis (Baylis Scanlon et al., 2008, J. Biol. Chem. 283, 26228-26240) and ATP synthesis with similar steady-state parameters. ATP
Galkin, Mikhail, Nakamoto, Robert
openaire   +1 more source

Functions of J‐domain proteins in mitochondrial protein biogenesis

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Mitochondrial biogenesis and functions depend on the import and assembly of more than 1000 proteins that are made as precursors on cytosolic ribosomes. The majority of these precursor proteins are transported from the ribosome to the translocase of the outer membrane (TOM complex), which constitutes the main entry site for mitochondrial ...
Vitasta Tiku, Georg Bossenz, Janine Kirstein, Thomas Becker   +3 more
wiley   +1 more source

scRNA-seq reveals ATPIF1 activity in control of T cell antitumor activity

OncoImmunology, 2022
ATP synthase inhibitory factor 1 (ATPIF1) is a mitochondrial protein with an activity in inhibition of F1Fo-ATP synthase. ATPIF1 activity remains unknown in the control of immune activity of T cells.
Genshen Zhong, Qi Wang, Ying Wang, Ying Guo, Meiqi Xu, Yaya Guan, Xiaoying Zhang, Minna Wu, Zhishan Xu, Weidong Zhao, Hongkai Lian, Hui Wang, Jianping Ye   +12 more
doaj   +1 more source

Genomic and Transcriptomic Insights Into the Autotrophic Metabolism on H2 + CO2 or CO of the Thermophilic Acetogenic Model Organism Moorella thermoacetica

Environmental Microbiology, Volume 28, Issue 4, April 2026.
Moorella thermoacetica is the model organism for elucidation of acetogenesis. The reduction of CO2 to acetate is well studied, but how redox carrier balancing and energy conservation are maintained during autotrophic growth and how H2 is oxidised remains enigmatic.
Florian P. Rosenbaum, Anja Poehlein, Rolf Daniel, Volker Müller   +3 more
wiley   +1 more source

New structural insights in chloroplast F1FO-ATP synthases

, 2020
Published by RWTH Aachen University ...
openaire   +2 more sources