Chimeric Ad5.F35 vector evades anti-adenovirus serotype 5 neutralization opposing GUCY2C-targeted antitumor immunity [PDF]
Journal for ImmunoTherapy of Cancer, 2020 Background Adenovirus serotype 5 (Ad5) is a commonly used viral vector for transient delivery of transgenes, primarily for vaccination against pathogen and tumor antigens.
Tingting Zhan +13 more
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Chimeric adenoviral (Ad5.F35) and listeria vector prime-boost immunization is safe and effective for cancer immunotherapy [PDF]
npj Vaccines, 2022 Strategies to augment immunity to self/neoantigens expressed by cancers are urgently needed to expand the proportion of patients benefiting from immunotherapy, particularly for GI cancers where only a fraction of patients respond to immunotherapies ...
John C. Flickinger +10 more
doaj +2 more sources
Synthetic Feed Attractants in European Seabass (Dicentrarchus labrax) Culture: Effects on Growth, Health, and Appetite Stimulation [PDF]
AnimalsSynthetic flavors from standardized processes have recently emerged as a promising and sustainable alternative to traditional feed attractants. In this study, two attractive (F25, cheese; F35, caramel) and one repulsive (F32-, coconut) synthetic flavors ...
Federico Conti +5 more
doaj +2 more sources
Substitution of Fishmeal With Soy Protein Concentrate on Growth, Organic Damage, Antioxidant, Transcriptome, and Metabolomics in Macrobrachium rosenbergii [PDF]
Aquaculture NutritionThe present study investigated growth performance, body composition, hepatic and intestinal morphology, biochemical indices, transcriptomic responses, and metabolomic profiles in giant freshwater prawn (Macrobrachium rosenbergii) fed six kinds of soy ...
Li Wang +10 more
doaj +2 more sources
Clinical impact of high-quality testing for peritoneal lavage cytology in pancreatic cancer [PDF]
Scientific ReportsIn pancreatic ductal adenocarcinoma (PDAC) patients, the importance of peritoneal lavage cytology, which indicates unresectability, remains controversial.
Masahiro Tanemura +9 more
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Silencing of APE1 enhances sensitivity of human hepatocellular carcinoma cells to radiotherapy in vitro and in a xenograft model. [PDF]
PLoS ONE, 2013 Resistance to radiotherapy is a key limitation for the treatment of human hepatocellular carcinoma (HCC). To overcome this problem, we investigated the correlation between radioresistance and the human apurinic/apyrimidinic endonuclease (APE1), a ...
Yanping Cun +7 more
doaj +1 more source
External aid behavior in the recipient economy: A probit regression for Africa
Journal of Economics and Management, 2022 Aim/purpose – External aid allocation by the donors in recent years has been fraught with instability and volatility. This has a negative consequence on the recipient economies particularly those that are highly aid-dependent.
Adediyan Aderopo Raphael +1 more
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Effects of Development Aid on Donor’s Exports: A Case of the Czech Republic
Review of Economic Perspectives, 2022 The main goal of foreign aid should be the support of developing regions; however, due to the rising international requirements on the amount of provided aid, donors start to focus on the benefits aid can bring them as well.
Dufková Gabriela, Šálek Pavel
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Proteomic analysis of seedling roots of two maize inbred lines that differ significantly in the salt stress response. [PDF]
PLoS ONE, 2015 Salinity is a major abiotic stress that limits plant productivity and quality throughout the world. Roots are the sites of salt uptake. To better understand salt stress responses in maize, we performed a comparative proteomic analysis of seedling roots ...
Dezhou Cui +13 more
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The role of foreign aid in the transformation of Iraq's society and economy
International Journal of Management and Economics, 2022 Foreign aid helps in transforming nations and ensuring that they attain economic development. Foreign aid levels in Iraq are higher than those of its oil-producing neighbors due to numerous factors that are discussed in the present study.
Jaber Hadi
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