Results 71 to 80 of about 811,714 (302)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Description of concept and first feasibility test results of a life support subsystem of the Botany Facility based on water reclamation [PDF]
The Botany Facility allows the growth of higher plants and fungi over a period of 6 months maximum. It is a payload planned for the second flight of the Eureca platform around 1990.
Loeser, H. R.
core +1 more source
Tracking Chart 2008 Asics in Turkey (Factory 2, September) [PDF]
, 2008 The FLA uses Tracking Charts to provide the public with information about the compliance situation of individual factories - the specific problems that were found by monitors and the action taken by participating companies in response to the findings ...
Fair Labor Association
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Consideration for UNOLS treatment of ORVs as Public Vessels [PDF]
, 2017 This document reviews the legal standards providing differential treatment of “public vessel” under federal regulations, including regulatory definitions of that term.
Hartmann, Mark
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Fusionskontrolle in dynamischen Netzsektoren am Beispiel des Breitbandkabelsektors: zugleich ein kritischer Beitrag zur Kartellrechtsdogmatik des Bundeskartellamts nach Iesy/Ish und TC/Ish und sektorspezifischen Regulierungskonsistenz seitens der Bundesnetzagentur [PDF]
The working report looks at the actual situation of the German broadband cable market in the context of merger control and sector specific regulation.
Abrar, Kamyar
core
Plain Meaning, Precedent, and Metaphysics: Interpreting the “Point Source” Element of the Clean Water Act Offense [PDF]
, 2015 This Article, the fourth in a series of five, examines the continuing struggles to define “point source” and “nonpoint source” under the Clean Water Act.
Miller, Jeffrey G.
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Scientific ReportsWe examine which decentralized finance architectures enable meaningful regulation by combining financial and computational theory. We show via deduction that a decentralized and permissionless Turing-complete system cannot provably comply with ...
Ben Charoenwong +2 more
doaj +1 more source