Results 51 to 60 of about 119,277,255 (280)
Anti-Depressive Effectiveness of Baicalin In Vitro and In Vivo
Molecules, 2019 Baicalin (BA), a major polyphenol compound isolated from the extracts of Scutellaria radix, has been previously reported to ameliorate depressive-like behaviors in mice with chronic unpredictable mild stress (CUMS). However, its underlying antidepressant
Li Liu +5 more
doaj +1 more source
Hydrogen Sulfide Donor GYY4137 Rescues NRF2 Activation in Respiratory Syncytial Virus Infection
Antioxidants, 2022 Respiratory syncytial virus (RSV) can cause severe respiratory illness in infants, immunocompromised, and older adults. Despite its burden, no vaccine or specific treatment is available. RSV infection is associated with increased reactive oxygen species (
Aline Haas de Mello +3 more
doaj +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Expression of the insulin-like growth factor-II/mannose-6-phosphate receptor in multiple human tissues during fetal life and early infancy [PDF]
, 1992 The insulin like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptor has been detected in many cells and tissues. In the rat, there is a dramatic developmental regulation of IGF-II/M6P receptor expression, the receptor being high in fetal and ...
Eisenmenger, Wolfgang +5 more
core +1 more source
, 2022 Biomarker identification is imperative for invasive breast carcinoma, which is more aggressive and associated with higher mortality and worse prognosis in younger patients (<45 years) than in older patients (>50 years).
Lam, AK +9 more
core +1 more source
Applied Sciences, 2022 Loquat (Eriobotrya japonica) leaf extract exhibits bioactive properties against a variety of diseases. However, it remains unclear whether loquat leaf extract can protect myoblasts from oxidative damage.
Young Hoon Kwon +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba +29 more
wiley +1 more source
Dynamic profiles of 25 serum biomarkers in acute myocardial infarction
Frontiers in Cardiovascular MedicineBackgroundAcute myocardial infarction (AMI) is a leading cause of cardiovascular mortality and perioperative complications in the elderly (>65 years).
Xuefeng Ai +9 more
doaj +1 more source
Modified insulin-like growth factor 1 containing collagen-binding domain for nerve regeneration
Neural Regeneration Research, 2018 Insulin-like growth factor 1 (IGF-1) is a potential nutrient for nerve repair. However, it is impractical as a therapy because of its limited half-life, rapid clearance, and limited target specificity.
Jian-an Li +7 more
doaj +1 more source
The role of endothelial biomarkers in predicting damp-heat syndrome in diabetic kidney disease
Journal of Traditional Chinese Medical Sciences, 2022 Objective: To explore the role of endothelial biomarkers in predicting damp-heat syndrome in diabetic kidney disease (DKD). Methods: A total of 183 patients with DKD were divided into 3 groups: the early DKD group, established DKD group, and advanced DKD
Zhenjie Chen +8 more
doaj +1 more source