Results 41 to 50 of about 1,628,545 (288)

The Allograft Inflammatory Factor-1 (AIF-1) homologous in Hirudo medicinalis (medicinal leech) is involved in immune response during wound healing and graft rejection processes [PDF]

Invertebrate Survival Journal, 2015
Allograft inflammatory factor-1 (AIF-1) is a 17 kDa cytokine-inducible calcium-binding protein that in Vertebrates plays an important role in allografts immune response.
T Schorn, F Drago2, M de Eguileor, R Valvassori, J Vizioli2, G Tettamanti, A Grimaldi   +6 more
doaj   +2 more sources

Candida albicans uses the surface protein Gpm1 to attach to human endothelial cells and to keratinocytes via the adhesive protein vitronectin. [PDF]

PLoS ONE, 2014
Candida albicans is a major cause of invasive fungal infections worldwide. Upon infection and when in contact with human plasma as well as body fluids the fungus is challenged by the activated complement system a central part of the human innate immune ...
Crisanto M Lopez, Reinhard Wallich, Kristian Riesbeck, Christine Skerka, Peter F Zipfel   +4 more
doaj   +1 more source

Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi

, 2010
Background: One virulence property of Borrelia burgdorferi is its resistance to innate immunity, in particular to complement-mediated killing. Serum-resistant B.
Teresia Hallström, Hallström Teresia, Christine Skerka, Beckhaus Tobias, Skerka, Christine, Karas Michael, Hannes Eberhardt, Michael Karas, Barbara Uzonyi, Corinna Siegel, Kraiczy Peter, Eberhardt, Hannes, Uzonyi Barbara, Zipfel, Peter F., Beckhaus, Tobias, Peter Kraiczy, Karas, Michael (Prof. Dr.), Stevenson, Brian, Peter F Zipfel, Stevenson Brian, Uzonyi, Barbara, Brian Stevenson, Peter F. Zipfel, Siegel, Corinna, Hallström, Teresia, Kraiczy, Peter, Tobias Beckhaus, Eberhardt Hannes, Skerka Christine, Wallich, Reinhard, Zipfel Peter F., Reinhard Wallich, Siegel Corinna, Karas, Michael, Wallich Reinhard   +34 more
core   +1 more source

Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain [PDF]

, 2005
Calpains are non-lysosomal, Ca2+-dependent cysteine proteases, which are ubiquitously distributed across cell types and vertebrate species. The rules that govern calpain specificity have not yet been determined.
Mann, Karlheinz, Mann, K., Ghosh, M., Machleidt, W., Machleidt, Werner, Siwanowicz, I., Ghosh, Madhumita, Holak, Tad A., Holak, T. A., Holak, T., Siwanowicz, Igor, Shanker, Sreejesh, Shanker, S.   +12 more
core   +1 more source

Hide and seek: how Lyme disease spirochetes overcome complement attack

Frontiers in Immunology, 2016
Overcoming the first line of the innate immune system is a general hallmark of pathogenic microbes to avoid recognition and to enter the human host.
Peter Kraiczy
doaj   +1 more source

Contribution of the infection-associated complement regulator-acquiring surface protein 4 (ErpC) to complement resistance of Borrelia burgdorferi [PDF]

, 2012
Borrelia burgdorferi evades complement-mediated killing by interacting with complement regulators through distinct complement regulator-acquiring surface proteins (CRASPs).
Teresia Hallström, Peter F. Zipfel, Zipfel, Peter F, Christine Skerka, Hallström, Teresia, Kraiczy, Peter, Skerka, Christine, Claudia Hammerschmidt, Wallich, Reinhard, Hammerschmidt, Claudia, Zipfel, Peter F., Reinhard Wallich, Peter Kraiczy, Stevenson, Brian, Brian Stevenson   +14 more
core   +1 more source

Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling

Frontiers in Pharmacology, 2020
Cardamonin (CD), a naturally occurring chalcone derived from the Alpinia species, has been shown to exert antioxidant and anti-inflammatory activity, but its role in the prevention of acetaminophen- (APAP-) induced hepatotoxicity remains elusive.
Qiushi Xu, Yunhui Fan, Juan J. Loor, Yusheng Liang, Xudong Sun, Hongdou Jia, Chenxu Zhao, Chuang Xu   +7 more
doaj   +1 more source

Calcium binding activity of the epidermal growth factor-like domains of the apicomplexan microneme protein EtMIC4

, 2005
Microneme proteins are secreted from apicomplexan parasites during invasion of host cells and they play crucial roles in parasite-host cell adhesion.
Gill, A C, Knott, V, Tomley, F M, Periz, J, Tomley, FM, Handford, P A, Gill, AC, Handford, Penelope, Handford, PA   +8 more
core   +1 more source

Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland [PDF]

, 2005
We have demonstrated that insulin-like growth factor binding protein-5 (IGFBP-5) production by mammary epithelial cells increases dramatically during forced involution of the mammary gland in rats, mice and pigs.
Beattie, J, Whitelaw C. B. A., ACCORSI, PIER ATTILIO, Hurley, W, Boutinaud, M, Kolb A., Allan G. A., Tonner, E, Wilde, C J, Boutinaud M., Wilde C. J., Beattie J., Accorsi, P A, Flint, D J, Flint D. J., Tonner E., Whitelaw, C B A, Hurley W., Kolb, A F, Allan, G J   +19 more
core   +1 more source

Anti-Depressive Effectiveness of Baicalin In Vitro and In Vivo

Molecules, 2019
Baicalin (BA), a major polyphenol compound isolated from the extracts of Scutellaria radix, has been previously reported to ameliorate depressive-like behaviors in mice with chronic unpredictable mild stress (CUMS). However, its underlying antidepressant
Li Liu, Yu Dong, Xin Shan, Lin Li, Baomei Xia, Hanqing Wang   +5 more
doaj   +1 more source