Results 21 to 30 of about 1,628,545 (288)

Gene expression patterns of insulin-like growth factor 1, insulin-like growth factor 2 and insulin-like growth factor binding protein 3 in human placenta from pregnancies with intrauterine growth restriction [PDF]

, 2011
Introduction: In this study, we compared insulin-like growth factor (IGF)-gene expression patterns and characteristics of glucose and insulin metabolism in human placenta from pregnancies with or without intrauterine growth restriction (IUGR).
Tóth, Katalin, Börzsönyi Balázs, Demendi Csaba, Balázs Börzsönyi, Börzsönyi, Balázs, Tóth Katalin, János Rigó Jr, Pajor, Attila, Rigó, János, Joó József, Gábor, Zsolt Nagy, Csaba Demendi, Rigó János, Pajor Attila, Mónika Csanád, Katalin Tóth, Demendi, Csaba, Csanád, Mónika, Nagy, Zsolt, Attila Pajor, József Gábor Joó, Nagy Zsolt, Csanád Mónika, Joó József Gábor   +23 more
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Aspf2 From Aspergillus fumigatus Recruits Human Immune Regulators for Immune Evasion and Cell Damage

Frontiers in Immunology, 2018
The opportunistic fungal pathogen Aspergillus fumigatus can cause life-threatening infections, particularly in immunocompromised patients. Most pathogenic microbes control host innate immune responses at the earliest time, already before infiltrating ...
Prasad Dasari, Iordana A. Shopova, Maria Stroe, Dirk Wartenberg, Hans Martin-Dahse, Niklas Beyersdorf, Peter Hortschansky, Stefanie Dietrich, Stefanie Dietrich, Zoltán Cseresnyés, Marc Thilo Figge, Marc Thilo Figge, Martin Westermann, Christine Skerka, Axel A. Brakhage, Axel A. Brakhage, Peter F. Zipfel, Peter F. Zipfel   +17 more
doaj   +1 more source

In vivo and in vitro protective effects of shengmai injection against doxorubicin-induced cardiotoxicity

Pharmaceutical Biology, 2022
Context Shengmai injection (SMI) has been used to treat heart failure.Objective This study determines the molecular mechanisms of SMI against cardiotoxicity caused by doxorubicin (DOX).Materials and methods In vivo, DOX (15 mg/kg) was intraperitoneally ...
Peng Zhou, Ge Gao, Chun-chun Zhao, Jing-ya Li, Jian-fei Peng, Shu-shu Wang, Rui Song, Hui Shi, Liang Wang   +8 more
doaj   +1 more source

Human PathogenicBorrelia spielmaniisp. nov. Resists Complement-Mediated Killing by Direct Binding of Immune Regulators Factor H and Factor H-Like Protein 1 [PDF]

Infection and Immunity, 2007
ABSTRACTBorrelia spielmaniisp. nov. has recently been shown to be a novel human pathogenic genospecies that causes Lyme disease in Europe. In order to elucidate the immune evasion mechanisms ofB. spielmanii, we compared the abilities of isolates obtained from Lyme disease patients and tick isolate PC-Eq17 to escape from complement-mediated ...
Herzberger, Pia, Siegel, Corinna, Skerka, Christine, Fingerle, Volker, Schulte-Spechtel, Ulrike, van Dam, Alje, Wilske, Bettina, Brade, Volker, Zipfel, Peter F., Wallich, Reinhard, Kraiczy, Peter   +10 more
openaire   +3 more sources

Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells [PDF]

, 2009
Insulin-like growth factor 1 (IGF1) Is Involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly.
Takahashi, Sumio, Takeuchi, Sakae, Kanayama, Munetoshi, Maekawa, Tetsuya   +3 more
core   +1 more source

Anti-inflammatory Effect of Lyophyllum ulmarium Fibrinolytic Enzyme on Macrophages [PDF]

Shipin Kexue
This study evaluated the anti-inflammatory effect of a fibrinolytic enzyme from Lyophyllum ulmarium (LUFE) on lipopolysaccharide-induced J774A.1 macrophages.
SU Xin, ZHANG Qing, WANG Jiayi, SHEN Minghua
doaj   +1 more source

Human Complement Factor H and Factor H-Like Protein 1 Are Expressed in Human Retinal Pigment Epithelial Cells

Ophthalmic Research, 2013
<b><i>Background:</i></b> A common haplotype in the gene for the regulator of the alternative pathway of complement activation factor H has been linked to individual predisposition to age- related macular degeneration (AMD). <b><i>Methods:</i></b> In this study, retinal pigment epithelial (RPE) cells, i.e.
Weinberger, Andreas, Eddahabi, Cordula, Carstesen, Dörthe, Zipfel, Peter F, Walter, Peter, Skerka, Christine   +5 more
openaire   +3 more sources

CLONING OF THE 1.4-kb mRNA SPECIES OF HUMAN COMPLEMENT FACTOR H REVEALS A NOVEL MEMBER OF THE SHORT CONSENSUS REPEAT FAMILY RELATED TO THE CARBOXY TERMINAL OF THE CLASSICAL 150-kDa MOLECULE [PDF]

, 1991
Three factor H mRNA species of 4.3 kb, 1.8 kb, and 1.4 kb are constitutively expressed in human liver. Having previously characterized full-length cDNA clones derived from the 4.3-kb and 1.8-kb factor mRNA, we report here the isolation and eucaryotic ...
Estaller, C., Schwaeble, W., Koistinen, V., Dierich, Manfred P., Weiss, Elisabeth H.   +4 more
core   +1 more source

Comparative transcriptome analysis reveals resistant and susceptible genes in tobacco cultivars in response to infection by Phytophthora nicotianae

Scientific Reports, 2021
Phytophthora nicotianae is highly pathogenic to Solanaceous crops and is a major problem in tobacco production. The tobacco cultivar Beihart1000-1 (BH) is resistant, whereas the Xiaohuangjin 1025 (XHJ) cultivar is susceptible to infection.
He Meng, Mingming Sun, Zipeng Jiang, Yutong Liu, Ying Sun, Dan Liu, Caihong Jiang, Min Ren, Guangdi Yuan, Wenlong Yu, Quanfu Feng, Aiguo Yang, Lirui Cheng, Yuanying Wang   +13 more
doaj   +1 more source

Identification and functional characterisation of Complement Regulator Acquiring Surface Protein-1 of serum resistant Borrelia garinii OspA serotype 4 [PDF]

, 2010
Background: B. burgdorferi sensu lato (sl) is the etiological agent of Lyme borreliosis in humans. Spirochetes have adapted themselves to the human immune system in many distinct ways.
Peter F. Zipfel, Dam, A.P. van, Schuijt, Tim J., Kraiczy, Peter, Nathalie D. van Burgel, Nathalie D. van Burgel, van Dam, Alje P., van Burgel Nathalie D, Burgel, N.D. van, Burgel, Nathalie D. van, Schuijt Tim J, Tim J. Schuijt, Kraiczy Peter, Schuijt, T.J., van Dam Alje P, Zipfel Peter F, Kraiczy, P., Zipfel, Peter F., Alje P. van Dam, Peter Kraiczy, Zipfel, P.F., Dam, Alje P. van, van Burgel, Nathalie D.   +22 more
core   +1 more source