Results 81 to 90 of about 119,277,255 (280)

Antagonistic Effect of Corn Protein Hydrolysate on Gastric Injury in Mice Induced by Helicobacter pylori Infection [PDF]

Shipin Kexue
The protective effects of corn protein hydrolysate (CPN) on gastric injury in mice induced by Helicobacter pylori infection were investigated. Healthy Kunming male mice were adaptively fed for seven days and randomly divided into six groups: normal ...
LI Guanlong, LIU Xiaolan, MIAO Zhengfei, ZHENG Xiqun
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis. [PDF]

, 2013
Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the gastrointestinal tract. Chronic infection of gastric epithelial cells by Helicobacter pylori (H. pylori) is a major risk factor for human gastric cancer (GC) where Cav1 is
Ivana Hitkova (401838), Ivana Hitkova, Matthias P. A. Ebert, Florian Anderl (183670), Thomas Kirchner (109827), Matthias P A Ebert, Roland M Schmid, Schmid, Roland M., Thomas Kirchner, Claus Schäfer, Roger Vogelmann (358771), Markus Gerhard (183676), Florian Anderl, Elke Burgermeister, Yuan, Gang, Simone Reu, Christoph Röcken (170345), Roland M. Schmid (130086), Ebert, Matthias P. A., Christoph Röcken, Reu, Simone, Schäfer, Claus, Gang Yuan, Vogelmann, Roger, Claus Schäfer (401841), Hitkova, Ivana, Anderl, Florian, Markus Gerhard, Roger Vogelmann, Simone Reu (401840), Röcken, Christoph, Gang Yuan (401839), Matthias P. A. Ebert (250492), Roland M. Schmid, Elke Burgermeister (401842), Kirchner, Thomas, Burgermeister, Elke, Gerhard, Markus, Yuan Gang, Burgermeister Elke, Anderl Florian, Kirchner Thomas, Hitkova, I;Yuan, G;Anderl, F;Gerhard, M;Kirchner, T;Reu, S;Röcken, C;Schafer, C;Schmid, RM;Vogelmann, R;Ebert, MP;Burgermeister, E, Schäfer Claus, Schmid Roland M., Gerhard Markus, Hitkova Ivana, Ebert Matthias P. A., Reu Simone, Röcken Christoph, Vogelmann Roger   +50 more
core   +2 more sources

Neuroprotective effects of hydrogen sulfide on BDNF, IGF-1, and oxidative stress in the hippocampus of high-fat diet rats

IBRO Neuroscience Reports
A high-fat diet (HFD) induces oxidative stress and reduces hippocampal neurotrophic factors, contributing to cognitive impairment. Hydrogen sulfide (H₂S) is an endogenous gaseous signaling molecule with recognized neuroprotective and antioxidant ...
Ronak Jarahi, Haneih Moradeian, Golnaz Azami, Boshra Ebrahimy, Iraj Salehi, Heresh Moridi   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Repairing Effect of Fucoxanthin on Non-alcoholic Fatty Liver Disease in Mice [PDF]

Shipin Kexue
Objective: To explore the repairing effect and underlying mechanism of fucoxanthin on non-alcoholic fatty liver disease (NAFLD) induced by a high-fat diet (HFD) in C57BL/6 mice.
REN Xiangyu, ZHENG Jiawen, TIAN Xiaoxiao, CAO Hongjie, LI Hangting, TANG Yunping, YANG Zuisu
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Regulation of human fibroblast insulin-like growth factor (IGF)-binding proteins by IGF-1 and cytokines, mechanisms of action and effects upon IGF bioactivity [PDF]

, 1995
PhDThe insulin-like growth factors, IGF-I and IGF-II, are ubiquitous polypeptide molecules that have mitogenic and metabolic actions in a wide variety of cell types, and consequently play a major role in mammalian growth and development.
Yateman, Martin Edward
core   +2 more sources

Acute Kidney Injury Biomarkers in Marathon Runners: Systematic Review and Meta-Analysis

Medicina
Background and Objectives: The objectives of this review were as follows: to measure changes in renal biomarker levels before, immediately after, and 24 h post-marathon; to identify promising biomarkers for the diagnosis of acute kidney injury; and to ...
Daniel-Corneliu Leucuța, Loredana-Ioana Trif, Oana Almășan, Ștefan Lucian Popa, Abdulrahman Ismaiel   +4 more
doaj   +1 more source