Results 141 to 150 of about 306,625 (170)

Opportunistic Genomic Screening for Familial Hypercholesterolemia to Improve Low-Density Lipoprotein Cholesterol: A Randomized Clinical Trial.

JAMA Netw Open
Vassy JL, Brunette CA, Yi T, Assimes TL, Christensen KD, Knowles JW, Sturm AC, Sun YV, Alexander N, Cardellino MP, Harrison A, Gerety HL, Pyatt M, Vered R, Wilson PWF, Natarajan P, Whitbourne SB, Gaziano JM, Muralidhar S, Danowski ME, Veterans Affairs Million Veteran Program.   +20 more
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A Factor H-Fc fusion protein competes with serum FH for binding to Staphylococcus aureus and boosts complement-mediated opsonization

The Journal of Immunology, 2021
Abstract Staphylococcus aureus is a significant human pathogen that causes a multitude of superficial and invasive infections worldwide. As antibiotic resistance is increasing, novel therapies are in dire need. As a master of immune evasion, S. aureus produces several virulence factors to persist in the host.
Megan A G Sage, Katelyn D Cranmer, Keith Wycoff, Julia A Sharp   +3 more
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Assignment of complement components C4 binding protein (C4BP) and factor H (FH) to human chromosome 1q, using cDNA probes

Annals of Human Genetics, 1988
SummaryUsing cDNA probes for Factor H (FH) and C4 binding protein (C4BP) on a panel of somatic cell hybrids, we show that both of these genes map to the long arm of chromosome 1.
Hing, S., Day, A. J., Linton, S. J., Ripoche, J., Sim, R. B., Reid, K. B M, Solomon, E.   +6 more
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Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes

Molecular Immunology, 2000
Complement factor H (fH) is a member of a family of proteins involved in the regulation of complement activation (RCA). These proteins share a common structural motif, the Short Consensus Repeat (SCR), which is structurally conserved among related genes and between phylogenetically divergent species.
D A, Male, R J, Ormsby, S, Ranganathan, E, Giannakis, D L, Gordon   +4 more
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fH-aHUS hemolytic agarose plate: A descendents of Sanchez-corral assay for a rapid diagnosis of hereditary and acquired factor H-related Atypical Hemolytic Uremic Syndrome

Journal of Scientific and Innovative Research, 2015
INTRODUCTION Hemolytic uremic syndrome (HUS) is not only known by its approved drug Eculizumab, the most expensive medicine up to now (An annual drug cost US $573,720 per patient), but also by its catastrophic outcomes (70% of patients progress to death or renal failure in less than 1 year after the onset). In the absence of repetitive infections, this
openaire   +1 more source

Complement factor H and FH related proteins associate with severity of invasive bacterial infections

Molecular Immunology, 2018
Anna Van Beek, Richard Pouw, Nina Schweintzger, Daniela Klobassa, Ariane Biebl, Manfred Sagmeister, Mieke Brouwer, Werner Zenz, Diana Wouters, Taco Kuijpers   +9 more
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Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Complement regulator factor H (fH) levels in CSF of mild cognitive impairment (MCI) cases depend on the Y402H polymorphism

Molecular Immunology, 2011
Hakobyan, S., Mulder, S.D., Heijst, J.A., van der Flier, W.M., Morgan, B.P., Veerhuis, R.   +5 more
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Characterization of the glomerular endothelial binding sites for full-length complement factor H (FH) and for FH19–20 and FH5–7 domains

Molecular Immunology, 2011
Rops, L.W.M.M., Lehtinen, M.J., Daha, M.R., Bakker, M.A., Haapasalo, K., Smith, R.J.H., Berden, J.H.M., Jokiranta, T.S., Vlag, J. van der   +8 more
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Evolving standards of care and new challenges in the management of HER2‐positive breast cancer

Ca-A Cancer Journal for Clinicians, 2020
Grace M Choong, Grace D Cullen, Ciara C O'sullivan   +2 more
exaly