Results 31 to 40 of about 38,180 (186)

Increased risk of venous thrombosis by AB alleles of the ABO blood group and Factor V Leiden in a Brazilian population

Genetics and Molecular Biology, 2009
Most cases of a predisposition to venous thrombosis are caused by resistance to activated protein C, associated in 95% of cases with the Factor V Leiden allele (FVL or R506Q).
Magaly B.P.L.V. Lima, Aldemir Branco de Oliveira-Filho, Júlia F. Campos, Fárida C.B.C. Melo, Washington Batista das Neves, Raul Antônio Morais Melo, José Alexandre Rodrigues Lemos   +6 more
doaj   +1 more source

Factor V G1691A (Leiden) is a major etiological factor in Egyptian Budd-Chiari syndrome patients

Turkish Journal of Hematology, 2011
OBJECTIVE: Budd-Chiari syndrome is a multifactorial disease in which several prothrombotic disorders may predispose patients to the development of thrombosis at this uncommon location (hepatic veins). The aim of this study was to determine the prevalence
Tawhida Y. Abdel Ghaffar, Solaf M. Elsayed, Mohamed A. Sakr, Ezzat S. Elsobky, Sara M. Abdelhakam, Said Yousuf, Yonca Eğin, Nejat Akar   +7 more
doaj   +3 more sources

Rastreamento familiar do fator V de Leiden: a importância da detecção de portadores heterozigotos Familiar tracking of factor V Leiden: the importance of detection in heterozygous carriers

Revista Brasileira de Hematologia e Hemoterapia, 2005
O fator de Leiden é uma mutação genética que predispõe seus portadores ao tromboembolismo venoso. O objetivo do estudo foi investigar a distribuição dos alelos em 21 membros da família de três pacientes portadores de trombose com a presença da mutação do
Eunice B. Carvalho, Maria I.M.C. Pardini, Rosângela A.R.R. Holanda, Gentil C. Galiza-Neto, Sílvia M.M. Magalhães, Maria H.S. Pitombeira, Milena V. Holanda, Ailton T. Fontenele-Filho, Silvia H. B. Rabenhorst   +8 more
doaj   +1 more source

Factor V Leiden Mutation and Stroke

Pediatric Neurology Briefs, 2001
The association of the factor V Leiden mutation and cerebrovascular disorder (CVD) in children is reviewed and the clinical features of 8 children with cerebral palsy (CP) and the Leiden mutation are described from the National Institute of Neurological ...
J Gordon Millichap
doaj   +1 more source

SV-IV Peptide1–16 reduces coagulant power in normal Factor V and Factor V Leiden

Journal of Translational Medicine, 2007
Native Factor V is an anticoagulant, but when activated by thrombin, Factor X or platelet proteases, it becomes a procoagulant. Due to these double properties, Factor V plays a crucial role in the regulation of coagulation/anticoagulation balance. Factor
Ferrazzi Paola, Quaglia Ilaria, Rota Lidia, Lepretti Marilena, Di Micco Biagio, Di Micco Gianluca, Di Micco Pierpaolo   +6 more
doaj   +1 more source

The Association between Preeclampsia and Defined Polymorphisms in Prothrombin and Coagulation Factor V Genes [PDF]

Journal of Kerman University of Medical Sciences, 2016
Background & Aims: Preeclampsia is one of the complications of pregnancy and a major cause of maternal mortality. Since, hypercoagulation is one of the risk factors, defined polymorphisms of V and II coagulation factors (G1691A and G20210A) may increase ...
Zohreh Salari, Nasrollah Saleh-gohari, Nushin Zainali, Neda Salmani-Cheharfarsakhi   +3 more
doaj  

Factor V Leiden mutation: An added risk in single ventricle palliation

Annals of Pediatric Cardiology, 2012
We present the case report of a child with Factor V Leiden mutation who underwent Fontan procedure. Thromboembolism is a widely recognized complication of the Fontan procedure and its modifications. Factor V Leiden mutation, being a hypercoagulable state,
R Saileela, C Shanthi, Ravi Agarwal, Raghavan Subramanyan, K M Cherian   +4 more
doaj   +1 more source

Factor V Leiden Mutation and its Impact on Pregnancy Complications

Acta Medica, 2011
Objective: The aim of this prospective study was to find the association between the factor V Leiden mutation and adverse pregnancy outcomes. Methods: This study is an analysis of a prospective observational study of the frequency of placenta-mediated ...
Ľubica Hammerová, Ján Chabada, Juraj Drobný, Angelika Bátorová   +3 more
doaj   +1 more source

Prevention of thromboembolic events after radical prostatectomy in patients with hereditary thrombophilia due to a factor V Leiden mutation by multidisciplinary coagulation management

Asian Journal of Urology
Objective: To examine the perioperative impact of factor V Leiden mutation on thromboembolic events' risk in radical prostatectomy (RP) patients. With an incidence of about 5%, factor V Leiden mutation is the most common hereditary hypercoagulability ...
Randi M. Pose, Sophie Knipper, Jonas Ekrutt, Mara Kölker, Pierre Tennstedt, Hans Heinzer, Derya Tilki, Florian Langer, Markus Graefen   +8 more
doaj   +1 more source

MATERNAL AND FETAL COMPLICATIONS OCCURRING IN HEREDITARY THROMBOPHILIA [PDF]

Romanian Journal of Pediatrics, 2017
Objective. To identify qualitative and quantitative changes involving coagulation factors engaged in maternal and fetal complications, to determine the level of correlation between them, and to highlight the involvement of hereditary thrombophilia among ...
Janina-Georgiana Nacea, Nicolae Cernea, Viorela Enachescu, Loredana Anghel, Constantin Kamal, Ion Cristian Efrem, Ana-Maria Patrascu, Ionela Rotaru   +7 more
doaj   +1 more source