Results 81 to 90 of about 788,607 (367)

Pituitary apoplexy in a patient with atrial fibrillation as a side effect of dabigatran treatment [PDF]

open access: yes, 2022
Atrial fibrillation (AF) is the most common heart rhythm abnormality usually present in elderly population significantly increasing the risk for thromboembolic incidents and therefore requiring the long-term treatment with anticoagulant agents.
Cvrtila, Dora, Dušek, Tina
core   +2 more sources

ESCRT III Regulates Lysosomal Perinuclear Clustering by Inhibiting Kinesin 1 Leading to Agnps Cytotoxicity in Human Cells

open access: yesAdvanced Materials Interfaces, EarlyView.
AgNPs cause significant damage upon entering the lysosomes of human fibroblasts, resulting in lysosomal transport disorders and the occurrence of perinuclear clustering (LPC) of lysosomes by promoting apoptosis that is accompanied by a reduction in the expression levels of ESCRT III and Kinesin 1 proteins.
Tiantian Liu   +7 more
wiley   +1 more source

Rivaroxaban: A New Oral Factor Xa Inhibitor [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2010
Rivaroxaban is a direct inhibitor of factor Xa, a coagulation factor at a critical juncture in the blood coagulation pathway leading to thrombin generation and clot formation. It is selective for human factor Xa, for which it has >10 000-fold greater selectivity than for other biologically relevant serine proteases (half-maximal ...
Susanne Roehrig   +5 more
openaire   +3 more sources

Safety and Efficacy of Rivaroxaban in Patients With Cardiac Implantable Electronic Devices:Observations From the ROCKET AF Trial [PDF]

open access: yes, 2017
Background: Although implantation of cardiac implantable electronic devices (CIEDs) in patients receiving warfarin is well studied, limited data are available on the use of oral factor Xa inhibitors in this setting.
Becker, Richard C   +13 more
core   +2 more sources

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

open access: yesAdvanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang   +14 more
wiley   +1 more source

Equation of motion coupled-cluster approach for intrinsic losses in x-ray spectra [PDF]

open access: yes, 2020
We present an equation of motion coupled cluster approach for calculating and understanding intrinsic inelastic losses in core level x-ray absorption spectra (XAS). The method is based on a factorization of the transition amplitude in the time-domain, which leads to a convolution of an effective one-body spectrum and the core-hole spectral function ...
arxiv   +1 more source

Anti-Xa Activity and Event Risk in Patients With Direct Factor Xa Inhibitors Initiated Early After Stroke.

open access: yesCirculation Journal, 2018
BACKGROUND Measuring anti-Xa activity (AXA) has been reported as useful for predicting future risk of hemorrhagic and ischemic events in stroke patients taking direct factor Xa inhibitors.
S. Wada   +12 more
semanticscholar   +1 more source

Simultaneous Monitoring of Tyrosinase and ATP in Thick Brain Tissues Using a Single Two‐Photon Fluorescent Probe

open access: yesAdvanced Science, EarlyView.
A single dual‐emission two‐photon fluorescent probe is designed for simultaneously tracking tyrosinase (TYR) and adenosine triphosphate (ATP). With the help of this probe, the intricate correlation and regulatory mechanism between TYR and ATP during oxidative stress is uncovered.
Hong Huang   +12 more
wiley   +1 more source

Energetic model of tumor growth [PDF]

open access: yes, 2004
A macroscopic model of the tumor Gompertzian growth is proposed. This approach is based on the energetic balance among the different cell activities, described by methods of statistical mechanics and related to the growth inhibitor factors. The model is successfully applied to the multicellular tumor spheroid data.
arxiv   +1 more source

Engineering the Immune Response to Biomaterials

open access: yesAdvanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam   +12 more
wiley   +1 more source

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