Results 151 to 160 of about 1,443,501 (316)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Minutes: Medical School Faculty Advisory Council, Sept. 6, 2005

open access: yes, 2005
Faculty advisory council to the Dean of the Medical School.University of Minnesota. Medical School Faculty Advisory Council. (2005). Minutes: Medical School Faculty Advisory Council, Sept. 6, 2005. Retrieved from the University Digital Conservancy, https:
University of Minnesota. Medical School Faculty Advisory Council
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Minutes: Medical School Faculty Advisory Council, Dec. 6, 2005

open access: yes, 2005
Faculty advisory council to the Dean of the Medical School.University of Minnesota. Medical School Faculty Advisory Council. (2005). Minutes: Medical School Faculty Advisory Council, Dec. 6, 2005. Retrieved from the University Digital Conservancy, https:/
University of Minnesota. Medical School Faculty Advisory Council
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Minutes: Medical School Faculty Advisory Council, May 21, 2007

open access: yes, 2007
Faculty advisory council to the Dean of the Medical School.University of Minnesota. Medical School Faculty Advisory Council. (2007). Minutes: Medical School Faculty Advisory Council, May 21, 2007. Retrieved from the University Digital Conservancy, https:/
University of Minnesota. Medical School Faculty Advisory Council
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

AI in UK Medical Education: A Framework for Curriculum Reform. [PDF]

open access: yesJMIR Med Educ
Gaur A   +6 more
europepmc   +1 more source

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