Results 71 to 80 of about 219,223 (326)

PARCUKU: A RELIGIOUS RITUAL OF THE FAK-FAK COMMUNITY

Al-Albab, 2013
Local Islam which is synonymous with the implementation of rituals is always interesting to discuss, either through free discussion or in the academic sphere, which will map out the speakers at both confronting and accommodating areas. Similarly, the Parcuku religious ritual of the Fak-Fak community gave rise to a wide range of supporting and opposing ...
openaire   +3 more sources

Mechano-transduction to muscle protein synthesis is modulated by FAK [PDF]

, 2018
We examined the involvement of focal adhesion kinase (FAK) in mechano-regulated signalling to protein synthesis by combining muscle-targeted transgenesis with a physiological model for un- and reloading of hindlimbs.
Durieux, Anne-Cecile, Flueck, Martin, Freyssenet, Damien, Klossner, Stephan   +3 more
core  

Projection Pursuit through $\Phi$-Divergence Minimisation [PDF]

, 2010
Consider a defined density on a set of very large dimension. It is quite difficult to find an estimate of this density from a data set. However, it is possible through a projection pursuit methodology to solve this problem.
Azé, Bosq, Cressie, Csiszár, Huber, Jacques Touboul, Liese, Pardo, Saporta, Scott, Vajda, Van der Vaart   +11 more
core   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

Liver epithelial focal adhesion kinase modulates fibrogenesis and hedgehog signaling

JCI Insight, 2020
Focal adhesion kinase (FAK) is an important mediator of extracellular matrix–integrin mechano-signal transduction that regulates cell motility, survival, and proliferation.
Yun Weng, Tyler J. Lieberthal, Vivian X. Zhou, Maya Lopez-Ichikawa, Manuel Armas-Phan, Tristan K. Bond, Miya C. Yoshida, Won-Tak Choi, Tammy T. Chang   +8 more
doaj   +1 more source

New insights into FAK phosphorylation based on a FAT domain-defective mutation. [PDF]

PLoS ONE, 2014
Mounting evidence suggests that the FAK N-terminal (FERM) domain controls FAK phosphorylation and function; however, little is known regarding the role of the C terminal (FAT) domain in FAK regulation. We identified a patient-derived FAK mutant, in which
Xuqian Fang, Xiangfan Liu, Ling Yao, Changqiang Chen, Jiafei Lin, Peihua Ni, Xinmin Zheng, Qishi Fan   +7 more
doaj   +1 more source

KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages [PDF]

, 2016
Among the strategies adopted by glioma to successfully invade the brain parenchyma is turning the infiltrating microglia/macrophages (M/MΦ) into allies, by shifting them toward an anti-inflammatory, pro-tumor phenotype.
Catalano, M, D'Alessandro, G, Di Angelantonio, S, Esposito, V, Esposito, V, Golia, MT, Grimaldi, A, Grössinger, EM, Limatola, C, Ragozzino, D, Santoro, A, Wulff, H   +11 more
core   +2 more sources

Cyclodextrin Conjugated α-Bisabolol Suppresses FAK Phosphorylation and Induces Apoptosis in Pancreatic Cancer [PDF]

, 2023
MIKIKO TAKEBAYASHI KANO, TOSHIO KOKURYO, Taisuke Baba, KIMITOSHI YAMAZAKI, Junpei Yamaguchi, Masaki Sunagawa, Atsushi Ogura, Nobuyuki Watanabe, Shunsuke Onoe, Kazushi Miyata, Takashi Mizuno, Keisuke Uehara, TSUYOSHI IGAMI, Yukihiro Yokoyama, Tomoki Ebata, Masato Nagino   +15 more
openalex   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

FAK deletion promotes p53-mediated induction of p21, DNA-damage responses and radio-resistance in advanced squamous cancer cells.

PLoS ONE, 2011
Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase that is elevated in a variety of human cancers. While FAK is implicated in many cellular processes that are perturbed in cancer, including proliferation, actin and adhesion dynamics ...
Kathryn Graham, Kim Moran-Jones, Owen J Sansom, Valerie G Brunton, Margaret C Frame   +4 more
doaj   +1 more source