Results 1 to 10 of about 50 (30)
Familial adenomatous polyposis [PDF]
Journal of British Surgery, 1994 Abstract Familial adenomatous polyposis (FAP) is an autosomal dominant condition resulting in the development of more than 100 adenomatous polyps in the large bowel. In addition, a number of extracolonic manifestations of the condition may occur.
W J, Campbell, R A, Spence, T G, Parks
+8 more sources
Familial adenomatous polyposis [PDF]
Best Practice & Research Clinical Gastroenterology, 2009 A multimodal approach of complementary techniques targeting primarily truncating, deletion and rearrangement mutations provides a robust screening protocol that identifies the vast majority of pathogenic germline APC gene mutations in FAP patients.
Finlay, Macrae, D, du Sart, S, Nasioulas
+7 more sources
Familial Adenomatous Polyposis [PDF]
Journal of Pediatric Genetics, 2016 Familial adenomatous polyposis (FAP), caused by a germline mutation in the adenomatous polyposis coli (APC) gene on chromosome 5q21, is an autosomal dominant disorder characterized by hundreds to thousands of adenomas throughout the gastrointestinal tract.
Alexia, Waller +2 more
openaire +3 more sources
Attenuated Familial Adenomatous Polyposis
Internal Medicine, 2023 A 36-year-old man was diagnosed with multiple gastric polyps by esophagogastroduodenoscopy. Subsequent colonoscopy identified two tubular adenomas, and computed tomography revealed subcutaneous tumors. Based on these findings, we suspected that gastric polyposis was associated with the APC gene, either attenuated familial adenomatous polyposis (AFAP ...
Eizuka, Makoto +8 more
openaire +2 more sources
Familial Adenomatous Polyposis
Annals of Medicine, 1989 Familial adenomatous polyposis is an autosomal dominant disease that includes early development of up to thousands of colorectal adenomas and several extracolonic manifestations. All untreated patients will develop colorectal adenocarcinoma. The treatment of choice is colectomy and ileorectal anastomosis, but restorative proctocolectomy may be ...
openaire +5 more sources
Familial adenomatous polyposis coli
Journal of the Belgian Society of Radiology, 2011 Background: A 53-year-old male patient with a familial history of colon carcinoma presented with stool changes and abdominal cramps. There was no weight loss nor signs of blood in the stool. An endoscopic colonoscopy procedure showed multiple rectocolic polyps but was incomplete due to a stenosing mass at the splenic flexure.
Boeren, K, Vankan, Y, Perdieus, D
openaire +5 more sources
Familial adenomatous polyposis
, 2023 Patients with familial adenomatous polyposis (FAP) develop hundreds to thousands of colorectal adenomas and have a 100% risk of developing colorectal cancer, if left untreated. Patients undergo (procto)colectomy and lifelong endoscopic surveillance to prevent cancer.Current guidelines on polyposis do provide general recommendations on endoscopic ...
openaire +2 more sources
Familial adenomatous polyposis.
The Ceylon medical journal, 1998 Familial adenomatous polyposis (FAP) is a rare disorder associated with less than 1% of colorectal carcinomas (CRCs). Since FAP is a potentially preventable cause of CRC clinicians should have an adequate knowledge of it to identify the disease and to manage the patient and family.
D C, de Silva, R, Fernando
openaire +1 more source
Some of the next articles are maybe not open access.
Familial Adenomatous Polyposis
The American Journal of the Medical Sciences, 2020Familial adenomatous polyposis is a hereditary polyposis syndrome characterized by colorectal polyposis and eventually cancer if untreated, as well as a variety of benign and malignant extra-colonic features. Genetic testing and counselling is crucial for patients.
Abhishek Bhurwal +2 more
+7 more sources