The prevalence of high dysplastic colonic adenomatous polyps in a 3 year endoscopic retrospective study from a single clinical center [PDF]
, 2017 Introduction: Many colon neoplastic tumors come from the malignancy of adenomatous polyps (70%-90%) that were not timely diagnosed in order to be resected.
Moldovan, Cosmin A. +2 more
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Clinical characterization and the mutation spectrum in Swedish adenomatous polyposis families [PDF]
, 2008 Background: The dominantly inherited condition familial adenomatous polyposis (FAP) is caused by germline mutations in the APC gene. Finding the causative mutations has great implications for the families.
Gunilla Kanter-Smoler +74 more
core +2 more sources
Familial Adenomatous Polyposis: Experience from a Study of 1164 Unrelated German Polyposis Patients [PDF]
, 2005 The autosomal-dominant precancerous condition familial adenomatous polyposis (FAP) is caused by germline mutations in the tumour suppressor gene APC.
Waltraut Friedl, Stefan Aretz
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Diagnostic imaging and CEUS findings in a rare case of Desmoid-type fibromatosis. A case report [PDF]
, 2018 Desmoid-type fibromatosis (DF), also known as aggressive fibromatosis, is a locally aggressive benign fibroblastic neoplasm that can infiltrate or recur but cannot metastasize.
De Felice, Carlo +6 more
core +1 more source
A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss-of-Function Polymorphisms in Indoleamine-2,3-Dioxygenase-2. [PDF]
, 2018 BACKGROUND: Variation in an individual\u27s genetic status can impact the development of pancreatic ductal adenocarcinoma; however, the majority of familial pancreatic cancers (FPC) cannot yet be attributed to a specific inherited mutation.
Brody, Jonathan +9 more
core +2 more sources
Cold snare polypectomy effectively reduces polyp burden in familial adenomatous polyposis [PDF]
, 2016 BACKGROUND AND STUDY AIMS: Familial adenomatous polyposis (FAP) is generally managed by colectomy, but in some cases surgery is delayed and polyp burdens are managed endoscopically.
Patel, Nedhi J. +2 more
core +1 more source
Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system. [PDF]
, 2003 The Apc(Min/+) mouse model and the azoxymethane (AOM) rat model are the main animal models used to study the effect of dietary agents on colorectal cancer. We reviewed recently the potency of chemopreventive agents in the AOM rat model (D. E.
Corpet, Denis E., Pierre, Fabrice
core +2 more sources
Perekondlik adenomatoosne polüpoos: ülevaade ja ühe perekonna haigusjuht [PDF]
, 2015 Perekondlik adenomatoosne polüpoos ( familial adenomatous polyposis, FAP) on kõige sagedasem päriliku polüpoosi sündroom ning haigusega kaasneb väga suur risk haigestuda jämesoolevähki.
Laidre, Piret +7 more
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Gene Expression Profiling in Familial Adenomatous Polyposis Adenomas and Desmoid Disease [PDF]
, 2007 Gene expression profiling is a powerful method by which alterations in gene expression can be interrogated in a single experiment. The disease familial adenomatous polyposis (FAP) is associated with germline mutations in the APC gene, which result in ...
Nikola A Bowden +2 more
core +1 more source
Children's International Polyposis (CHIP) study : a randomized, double-blind, placebo-controlled study of celecoxib in children with familial adenomatous polyposis [PDF]
, 2017 Objective: To evaluate the efficacy and safety of celecoxib versus placebo in the prevention and treatment of colorectal polyposis in children with familial adenomatous polyposis (FAP).
Berger, Manuela F +9 more
core +2 more sources