Results 61 to 70 of about 34,604,755 (154)

Spreading depolarization and its influence on epileptiform activity

Epilepsia, Volume 67, Issue 3, Page 1078-1089, March 2026.
Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque, Rüdiger Köhling, Massimo Avoli   +2 more
wiley   +1 more source

Comprehensive assessment of erenumab efficacy in participants with high‐frequency episodic migraine with at least one previously failed preventive treatment: The EMBRACE study

Headache: The Journal of Head and Face Pain, Volume 66, Issue 3, Page 658-671, March 2026.
Abstract Objective To evaluate the effect of erenumab treatment beyond monthly migraine days in patients with high‐frequency episodic migraine who did not respond to at least one previous migraine preventive treatment. Background Reduction in monthly migraine days has been the efficacy standard for migraine preventive treatments; however, it does not ...
Gabriel Paiva da Silva Lima, Renata Rao, Gyöngyi Szabó, Sebastian Szklener, Cristina Tassorelli, Marcin Nastaj, Denise E. Chou, Ani C. Khodavirdi, Mahan Chehrenama, Yineng Zhu, Ajay K. Bhatia, David W. Dodick   +11 more
wiley   +1 more source

‘What's in a Name?’ Naming Genetically Determined Movement Disorders: Gap and Controversy

Movement Disorders, Volume 41, Issue 2, Page 342-350, February 2026.
Abstract In 2016, the International Parkinson and Movement Disorder Society (MDS) Task Force for Genetic Nomenclature in Movement Disorders laid out a new proposal for naming genetically determined movement disorders. This proposal sought to address the difficulties arising from the practical usage of numbered loci (eg, DYT1, DYT2, DYT3, etc.) as names
Connie Marras, Alberto Albanese, Mark Hallett, Christine Klein, Katja Lohmann, the Genetic Nomenclature in Movement Disorders Study Group Steering Committee, Christos Ganos, Sarah Camargos, Anthony E. Lang, Darius Ebrahimi‐Fakhari, Claudia Del Gamba, Bart van de Warrenburg, Lakshya Basumatary, Lara Lange, Diana Olszewska, Zhidong Cen, Kishore Kumar, Mohamed Zahir, Carolyn Sue, H.A. Jinnah   +19 more
wiley   +1 more source

Trigeminal neuralgia, migraine and sympathetic hyperactivity in a patient with Parry–Romberg syndrome [PDF]

, 2006
Parry–Romberg syndrome is a rare disorder of unknown aetiology that involves slowly progressive but self-limited wasting of subcutaneous tissues on one side of the face, usually in the distribution of a branch of the trigeminal nerve.
Drummond, P.D., Finch, P.M., Hassard, S.
core  

Monozygotic twin sisters discordant for familial hemiplegic migraine [PDF]

, 2013
Background: The high concordance rate of migraine in monozygotic twin pairs has long been recognised. In the current study, we present a monozygotic twin pair discordant for familial hemiplegic migraine (FHM).
Brandão, A., Rui Barreto, Cristina Ramos, Barros, J., Jorge Sequeiros, Damásio, J., Ana Filipa Brandão, Barreto, R., Joana Damásio, Isabel Alonso, Joana Domingos, Ramos, C., Lemos, C., Pereira-Monteiro, J., Carolina Lemos, Domingos, J., José Pereira-Monteiro, Sequeiros, J., Alonso, I., José Barros   +19 more
core   +2 more sources

Cortical synaptic transmission in CaV2.1 knockin mice with the S218L missense mutation which causes a severe familial hemiplegic migraine syndrome in humans.

Frontiers in Cellular Neuroscience, 2015
Familial hemiplegic migraine type 1 (FHM1) is caused by gain-of-function mutations in CaV2.1 (P/Q-type) Ca2+ channels. Knockin (KI) mice carrying the FHM1 R192Q missense mutation show enhanced cortical excitatory synaptic transmission at pyramidal cell ...
Dania eVecchia, Angelita eTottene, Arn M.J.M. van den Maagdenberg, Daniela ePietrobon   +3 more
doaj   +1 more source

Migraine and patent foramen ovale: correlation, coexistence, dependence. A narrative review

Headache: The Journal of Head and Face Pain, Volume 66, Issue 1, Page 307-321, January 2026.
Plain Language Summary This review looked at what scientists know about the connection between migraine and a small heart opening called a patent foramen ovale (PFO). It showed that people with migraine, especially with aura, often have PFO, but it is not certain whether closing this heart opening helps prevent strokes in these patients.
Olga Grodzka, Michał Borończyk, Anna Zduńska, Julia Węgrzynek‐Gallina, Izabela Domitrz, Anetta Lasek‐Bal   +5 more
wiley   +1 more source

Variable manifestations of familial hemiplegic migraine associated with reversible cerebral edema in children

, 2012
Three children with familial hemiplegic migraine presented with right-sided weakness, speech difficulty, altered mental status, and gait abnormalities.
Sharp, Gregory B, Asghar, Sheila J, Glasier, Charles, Milesi-Hallé, Alessandra, Kaushik, Chavvi   +4 more
core   +1 more source

Molecular Diagnosis in a Specialised Neurogenetic Clinic With Access to Whole‐Genome Sequencing

Acta Neurologica Scandinavica, Volume 2026, Issue 1, 2026.
Background Rare diseases, collectively affecting 1 in 17 people in the United Kingdom and Ireland, require coordinated care. Specialised multidisciplinary clinics offer a streamlined approach for diagnosis and management of rare neurogenetic disorders.
Patrick B. Moloney, Nicholas W. Wood, Rob Rouhl   +2 more
wiley   +1 more source

Familial hemiplegic migraine: a new gene in an italian family [PDF]

, 2019
Hemiplegic migraine (HM) is a rare form of migraine characterized by severe attacks of unilateral and pulsating headache (associated with photophobia, phonophobia or nausea).
Stefano Castellana3, Pietro Palumbo1#, Orazio Palumbo1#, Grazia Pastorino2, Mazza, Tommaso, Palumbo, Pietro, Felicia Operto, Francesca, Giangennaro Coppola, Castellana, Stefano, Carella, Massimo, Coppola, Giangennaro, Tommaso Mazza3, Palumbo, Orazio, DI MURO, ESTER, Pastorino, Grazia, Francesca Felicia Operto2, Ester Di Muro1, Tommaso Biagini3, 4, Massimo Carella, Leone, Maria Pia, Maria Pia Leone1, Biagini, Tommaso   +22 more
core   +1 more source