Results 91 to 100 of about 52,688 (314)

Schisantherin A: Remodeling Gut Microbiota to Activate the Gut–Immune–Neural–Adipose Axis for Thermogenesis

open access: yesiNew Medicine, EarlyView.
ABSTRACT The global obesity epidemic necessitates safe and effective strategies to enhance energy expenditure. Schisantherin A (Sin A), a lignan derived from Schisandra chinensis, has demonstrated metabolic benefits, yet its systemic mechanism remains unclear.
Ling Yin
wiley   +1 more source

Cost effectiveness of cascade testing for familial hypercholesterolaemia, based on data from familial hypercholesterolaemia services in the UK [PDF]

open access: yes, 2017
Peer reviewedPublisher ...
Cather, Moyra   +6 more
core   +2 more sources

Pulsatility Assessment of Cerebral Perforating Arteries Using Submillimeter‐Resolution Dual‐VENC Phase‐Contrast MRI at 3T

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Dysfunction of cerebral perforating arteries is a major contributor to cerebral small vessel disease. Developing a reliable MRI technique for assessing cerebral perforating arteries on widely accessible 3T systems would be advantageous.
Jianing Tang   +7 more
wiley   +1 more source

Criteria for Diagnosis of Familial Hypercholesterolemia: A Comprehensive Analysis of the Different Guidelines, Appraising their Suitability in the Omani Arab Population

open access: yesOman Medical Journal, 2014
Subjects with Familial hypercholesterolemia are at increased risk for cardiac events such as premature myocardial infarction and early death from coronary heart disease, especially in patients with severe forms of the disease if left unattended ...
Khalid Al-Rasadi   +6 more
doaj   +1 more source

The role of statin drugs in combating cardiovascular diseases –A review [PDF]

open access: yes, 2011
Statins clearly confer substantial benefit in people with established cardiovascular (CV) disease. Increased cholesterol levels have been associated with cardiovascular diseases (CVD), and statins are therefore used in the prevention of these diseases ...
Suresh Pichandi , Palanisamy Pasupathi, Y.Yagneswara Rao, Jawahar Farook, Athimoolam Ambika, Babu Shankar Ponnusha , Sathiyamoorthy Subramaniyam, Rajaram Virumandy, Boopathi subramaniyam Int J Cur Sci Res.
core  

No significant improvement of cardiovascular disease risk indicators by a lifestyle intervention in people with familial hypercholesterolemia compared to usual care: results of a randomised controlled trial [PDF]

open access: yes, 2012
Background: People with Familial Hypercholesterolemia (FH) may benefit from lifestyle changes supporting their primary treatment of dyslipidaemia. This project evaluated the efficacy of an individualised tailored lifestyle intervention on lipids (low ...
Broekhuizen, K.   +5 more
core   +4 more sources

Maralixibat for the treatment of severe xanthomas in two children with Alagille syndrome: Case reports

open access: yesJPGN Reports, EarlyView.
Abstract Alagille syndrome (ALGS) is a rare, autosomal dominant disorder which presents with a broad range of clinical manifestations, including cholestatic pruritus. A unique manifestation of ALGS is the presence of xanthomas in 24%–42% of patients, which can lead to liver transplantation.
Geetanjali Bora   +2 more
wiley   +1 more source

The 1(st) and the 2(nd) Italian Consensus Conferences on low-density lipoprotein-apheresis. A practical synopsis and update [PDF]

open access: yes, 2016
The clinical indications and guidelines for low-density lipoprotein (LDL)-apheresis set by the 1(st) Italian Consensus Conference held in Ostuni in 1990 and completed in 1992, but never published, are reported schematically.
Stefanutti, Claudia
core   +1 more source

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

open access: yesLipids, EarlyView.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao   +5 more
wiley   +1 more source

Towards Comprehensive Chronic Disease Control: Prevention, Early Detection, and Integrated Management

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Chronic non‐communicable diseases (NCDs), including cardiovascular disease, diabetes, cancer, and chronic respiratory conditions, represent the leading causes of morbidity and mortality worldwide. This review examines comprehensive strategies across the continuum of care (from primary prevention and early screening to timely diagnosis ...
Ping Sun, Zhengwei Wan, Yuping Liu
wiley   +1 more source

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