Results 81 to 90 of about 52,688 (314)

Familial hypercholesterolemia in Iceland. Review and outcome of family screening [PDF]

, 2008
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenFamilial hypercholesterolemia is a genetic disorder causing lifelong elevation of cholesterol and severely increased risk of coronary heart disease ...
Bolli Þórsson, Gunnar Sigurðsson, Guðrún Þorvaldsdóttir, Vilmundur Guðnason   +3 more
core  

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Establishment of a human induced pluripotent stem cell line from a patient with familial hypercholesterolemia carrying a frameshift mutation in LDLR gene

Stem Cell Research
Familial hypercholesterolemia is an autosomal dominant genetic disorder that often leads to abnormally high cholesterol levels in the body, which is closely related to early-onset coronary heart disease.
Yongjuan Ruan, Xiaowei Li, Jianzeng Dong, Youjian Zhang   +3 more
doaj   +1 more source

Evidence for a third genetic locus causing familial hypercholesterolemia: a non-LDLR, non-APOB kindred1

Journal of Lipid Research, 1999
Monogenically inherited hypercholesterolemia is most commonly caused by mutations at the low density lipoprotein receptor (LDLR) locus causing familial hypercholesterolemia (FH) or at the apolipoprotein B (APOB) locus causing the disorder familial ...
L. Haddad, I.N.M. Day, S. Hunt, R.R. Williams, S.E. Humphries, P.N. Hopkins   +5 more
doaj   +1 more source

A functional polymorphism in the glucocorticoid receptor gene and its relation to cardiovascular disease risk in familial hypercholesterolemia [PDF]

, 2006
Context: Individuals with the functional ER22/23EK variant in the glucocorticoid receptor gene are relatively resistant to the downstream consequences of glucocorticoids.
Dallinga-Thie, G.M. (Geesje), Defesche, J.C. (Joep), Kastelein, J.J.P. (John), Koeijvoets, K.C.M.C. (Kristel), Lamberts, S.W.J. (Steven), Rossum, E.F.C. (Liesbeth) van, Sijbrands, E.J.G. (Eric), Steyerberg, E.W. (Ewout)   +7 more
core   +1 more source

Similar content of phospholipids and gangliosides in normal and homozygous familial hypercholesterolemia fibroblasts.

Journal of Lipid Research, 1978
The cellular content of total and individual phospholipids and gangliosides was measured in fibroblasts cultured from four normal subjects, three patients with lysosomal lipid storage diseases, and two subjects with homozygous familial ...
P H Fishman, R M Bradley, M S Brown, J R Faust, J L Goldstein   +4 more
doaj   +1 more source

Nutritional status of children with familial hypercholesterolemia

, 2021
D. A. Polunina, M.E. Bagaeva, E.V. Pavlovskaya, Т.В. Строкова   +3 more
openalex   +1 more source

The UK Paediatric Familial Hypercholesterolaemia Register: preliminary data [PDF]

, 2016
BACKGROUND: The National Institute for Health and Care Excellence 2008 guidelines on the treatment and management of familial hypercholesterolaemia (FH) recommend that children with FH should be considered for statin treatment by the age of 10 years. The
Cooper, J, FH Paediatric Register Steering Group,, Humphries, SE, Ramaswami, U   +3 more
core   +1 more source

Body mass index and colorectal cancer recurrence and mortality: A nationwide cohort study in Denmark

International Journal of Cancer, EarlyView.
What's New? Obesity may worsen colorectal cancer prognosis, but the existing evidence remains inconclusive. This large nationwide cohort study comprehensively assessed how BMI interacts with demographic, clinical, and socioeconomic factors to influence colorectal cancer prognosis.
Cathrine F. Hjorth, Maja H. Olsen, Sinna P. Ulrichsen, Jesper Nors, Jannik Wheler, Signe Borgquist, Lene H. Iversen, Susanne O. Dalton, Deirdre Cronin‐Fenton   +8 more
wiley   +1 more source