Results 81 to 90 of about 1,073,734 (264)
Crossover of the dimensions of work-family and family-work conflict in couples: Protocol for a qualitative study. [PDF]
PLoS One, 2023 Smoktunowicz E +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Family-Work Conflict and Successful Aging at Work of Employees in Manufacturing Enterprises in North China. [PDF]
Psychol Res Behav Manag, 2023 Ma H, Zhao C.
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Crossover specificity of team-level work-family conflict to individual-level work-family conflict
, 2009 Purpose – this study aims to investigate the crossover specificity of team-level stressors to individual-level work-family conflict.design/methodology/approach – the paper takes the form of a multilevel analyses with data from 428 employees of a dutch ...
Work and Organizational Psychology: Occupational Health Psychology +4 more
core +1 more source
The integrative relationship between work–family conflict and turnover intention: a meta-analysis
Frontiers in Public HealthThe impact of work–family conflict on employee turnover intention has become a significant topic in organizational behavior research. However, existing findings show significant discrepancies, lacking systematic quantitative integration.
Guanghua Li +5 more
doaj +1 more source
Exploring the Relationship Between Work-Family Conflict, Family-Work Conflict and Job Embeddedness: Examining the Mediating Role of Emotional Exhaustion. [PDF]
Psychol Res Behav Manag, 2023 Dukhaykh S.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2010 This study investigated the relationship between the availability of, and the use of, work-family balance policies offered by organisations and family-supportive organisational perception (FSOP), work-to-family conflict, continuance and affective ...
Herlin, Paula Kristina
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source