Results 101 to 110 of about 106,589 (211)

Interaction between the Lentil Lipid Transfer Protein Lc-LTP2 and Its Novel Signal Ligand PI(4,5)P2

Membranes, 2020
It is known that plant lipid transfer proteins (LTPs) bind a broad spectrum of ligands including fatty acids (FAs), phospho- and glycolipids, acyl-coenzyme A and secondary metabolites.
Daria Melnikova, Ivan Bogdanov, Tatiana Ovchinnikova, Ekaterina Finkina   +3 more
doaj   +1 more source

Cell migration on material-driven fibronectin microenvironments [PDF]

, 2017
Cell migration is a fundamental process involved in a wide range of biological phenomena. However, how the underlying mechanisms that control migration are orchestrated is not fully understood.
Cantini, M., Dalby, M.J., Grigoriou, E., Petersen, A., Salmeron-Sanchez, M.   +4 more
core   +1 more source

TLR3 Deficiency Leads to a Dysregulation in the Global Gene-Expression Profile in Murine Oviduct Epithelial Cells Infected with Chlamydia muridarum [PDF]

, 2019
OBJECTIVE Describe the implementation and effects of Mobile Acute Care for Elders (MACE) consultation at a Veterans Affairs Medical Center (VAMC). DESIGN Retrospective cohort analysis.
Derbigny, Wilbert A, Kumar, Ramesh
core   +2 more sources

The C-terminal region of hepatitis C core protein is required for Fas-ligand independent apoptosis in Jurkat cells by facilitating Fas oligomerization

Virology, 2003
Hepatitis C virus (HCV) is remarkable for its ability to establish persistent infection. Studies suggest that HCV core protein modulates immune responses to viral infection and can bind Fas receptor in vitro. To further examine the role of HCV core protein in Fas signaling, full-length (aa 1-192) and truncated (aa 1-152) HCV core proteins were ...
Moorman, Jonathan P., Prayther, Deborah, McVay, Derek, Hahn, Young S., Hahn, Chang S.   +4 more
openaire   +3 more sources

Apoptosis and apoptosis-related proteins (Fas, Fas ligand, Blc-2, p53) in lymphoid elements of human ovarian tumors.

European journal of gynaecological oncology, 2000
Different types of lymphocytes have different roles in tumor suppression. Thus, their expression of apoptosis-related proteins (ARP - Fas and Fas ligand, bcl-2, p53) in lymphocytes and their apoptosis were analyzed immunohistochemically in ovarian tumors of different grades.
H, Ben-Hur, P, Gurevich, M, Huszar, A, Ben-Arie, V, Berman, Y, Tendler, O, Zinder, R, Tchanishev, S, Gershon, G, Mor, Y, Zaltsman, F, Kohen, I, Zusman   +12 more
openaire   +1 more source

Low concentration of ethanol induce apoptosis in HepG2 cells: role of various signal transduction pathways

International Journal of Medical Sciences, 2006
As we previously demonstrated in human hepatocellular carcinoma (HepG2) cells, ethanol at low concentration triggers the Fas apoptotic pathway. However, its role in other intracellular signaling pathways remains unknown. Therefore, the aim of the present
Francisco Castaneda, Sigrid Rosin-Steiner
doaj  

The role of Fas ligand protein in the oxidative stress induced by azoxymethane on crypt colon of rats O papel da proteína ligante Fas no estresse oxidativo induzido pelo azoximetano em criptas do colo de ratos

Acta Cirúrgica Brasileira, 2010
PURPOSE: To study the protein Fas ligand (FasL) on the expression of apoptosis, using a model of oxidative stress induced by azoxymethane (AOM), in the crypt of colon in rats.
Luiz Antonio Maksoud Bussuan, Djalma José Fagundes, Guido Marks, Priscila Maksoud Bussuan, Roberto Teruya   +4 more
doaj   +1 more source

Cell death and life in cancer: mathematical modeling of cell fate decisions

, 2011
Tumor development is characterized by a compromised balance between cell life and death decision mechanisms, which are tighly regulated in normal cells.
Barillot, Emmanuel, Calzone, Laurence, Fourquet, Simon, Tournier, Laurent, Zinovyev, Andrei   +4 more
core   +2 more sources

Cell death pathways as therapeutic targets in rhabdomyosarcoma [PDF]

, 2012
Resistance of rhabdomyosarcoma to current therapies remains one of the key issues in pediatric oncology. Since the success of most cytotoxic therapies in the treatment of cancer, for example, chemotherapy, depends on intact signaling pathways that ...
Fulda, Simone
core   +1 more source

Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein

Blood, 2010
AbstractAutoimmunity is a surprisingly common complication of primary immunodeficiencies, yet the molecular mechanisms underlying this clinical observation are not well understood. One widely known example is provided by Wiskott-Aldrich syndrome (WAS), an X-linked primary immunodeficiency disorder caused by mutations in the gene encoding the WAS ...
Nikolay P, Nikolov, Masaki, Shimizu, Sophia, Cleland, Daniel, Bailey, Joseph, Aoki, Ted, Strom, Pamela L, Schwartzberg, Fabio, Candotti, Richard M, Siegel   +8 more
openaire   +3 more sources