Results 151 to 160 of about 105,192 (298)
iNew Medicine, EarlyView.ABSTRACT The molecular mechanisms underlying the development of metabolic‐dysfunction‐associated steatotic liver disease (MASLD) are essential for developing appropriate treatments. The purpose of this study was to establish an MASLD model in mice with rapid and consistent progression.
Ting‐Ting Chen +10 more
wiley +1 more source
Journal of the Chinese Chemical Society, EarlyView.This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel +2 more
wiley +1 more source
A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma. [PDF]
J Neuroinflammation, 2019 Krishnan A +4 more
europepmc +1 more source
Reconceptualizing Aplastic Anemia—Seed, Worm, Soil
Journal of Clinical Laboratory Analysis, EarlyView.Aplastic anemia (AA) encompasses a group of hematological syndromes often misdiagnosed, resulting in a decrease in the overall blood cell count and representing a form of bone marrow failure. We reinterpret AA based on the “seed, worm, and soil” doctrine.
Xintong Xu +4 more
wiley +1 more source
IL-1β Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene. [PDF]
Front Cell Dev Biol, 2018 Thiyagarajan D +8 more
europepmc +1 more source
Lipid Metabolism, Lipogenesis, and Resistance to Third Generation EGFR‐TKIs
Journal of Clinical Laboratory Analysis, EarlyView.Cancer metabolism has emerged as a critical area of study in cancer research, offering insights into the complex mechanisms underlying tumor growth and development. Lipid metabolic reprogramming, especially the dynamic balance between fatty acid synthesis and fatty acid oxidation, plays significant roles in tumor progression. ABSTRACT Background Cancer
Wenhao Luo +5 more
wiley +1 more source
Journal of Raman Spectroscopy, EarlyView.Robust quantification in noncontact Raman sensing requires dedicated correction of working distance dependent background effects, while laser power variations are readily stabilized using internal reference signals. Chemically relevant Raman intensity can be preserved for bulk composition measurements, under variable laser power and working distance ...
Tiril Aurora Lintvedt +3 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.Physiological changes during pregnancy can trigger or worsen dermatological conditions, yet evidence‐based guidance for safe management remains limited. In a cross‐sectional survey of 273 pregnant women, 33.7% reported having a skin disease, and 56% experienced worsening of symptoms.
Frederikke Seeberg +4 more
wiley +1 more source
, 2017 Elizabeth DE Papathanassoglou,1,* Meropi DA Mpouzika,2,* Margarita Giannakopoulou,3 Evangelos Bozas,3 Nicos Middleton,2 George Tsiaousis,2 Andreas Karabinis4,5 1Faculty of Nursing, University of Alberta, Edmonton, AB, Canada; 2Department of Nursing ...
Karabinis A +6 more
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