Results 251 to 260 of about 105,192 (298)

Introduction to the symposium on reproducibility and replicability in economics: Part I

Economic Inquiry, Volume 63, Issue 2, Page 335-337, April 2025.
Farasat A. S. Bokhari, Abel Brodeur, Michalis Drouvelis   +2 more
wiley   +1 more source

Receptor-mediated apoptosis in B cells From the regulation of B Cell survival to potential novel approaches for lymphoma therapy [PDF]

Eeva, Jonna
core  

Fas receptor-mediated apoptosis: a clinical application?

Journal of Pathology, 2002
Fas is a membrane protein belonging to the death receptor family. Cross-linking of Fas by its ligand, FasL, or agonistic anti-Fas antibodies, induces apoptosis of cells expressing Fas on the membrane by triggering a cascade of caspases.
Elisabeth G E De Vries, Steven De Jong
exaly   +2 more sources

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Inhibition of Fas Receptor Endocytosis Sensitizes Cancer Cells to Fas-induced Apoptosis

European Journal of Cancer, 2022
Abstract Fas (CD95/APO-1) is a transmembrane death receptor that transduces apoptotic signals upon binding to its ligand and assembling into a death-inducing signaling complex (DISC) ( 1, 2 ).
Mehmet H. Kural, Umidahan Djakbarova, Bilal Cakir, Yoshiaki Tanaka, Yasaman Madraki, Hong Qian, Jinkyu Park, Lorenzo R. Sewanan, Comert Kural, Laura E. Niklason   +9 more
openaire   +2 more sources

Fas ligand: receptor or ligand?

Apoptosis, 1999
In this review, we chronicle the discovery, biochemical characterization, and assignment of Fas (CD95) as receptor and Fas Ligand (FasL, CD95L) as ligand. We review the functional descriptions of the molecules as death-inducing receptor and ligand or as mediators of cell division and/or growth arrest.
M K, Newell, J, Desbarats
openaire   +2 more sources

Fas receptor expression on B‐lineage cells

European Journal of Immunology, 1995
AbstractMice homozygous for the lpr mutation have B and T cell defects and develop autoantibodies, suggesting that lpr plays a role in their genesis. The lpr defect has been identified as a mutation in the apoptosis‐associated Fas receptor (FasR) gene.
L, Mandik, K A, Nguyen, J, Erikson
openaire   +2 more sources

Fas receptor‐mediated apoptosis: a clinical application?

The Journal of Pathology, 2001
AbstractFas is a membrane protein belonging to the death receptor family. Cross‐linking of Fas by its ligand, FasL, or agonistic anti‐Fas antibodies, induces apoptosis of cells expressing Fas on the membrane by triggering a cascade of caspases. Since many different tumours express Fas on their membrane, targeting Fas‐mediated apoptosis by anti‐Fas ...
Tineke, Timmer, Elisabeth G E, de Vries, Steven, de Jong   +2 more
openaire   +2 more sources

Soluble Fas receptor and soluble Fas ligand in the serum of women with uterine tumors

Apoptosis, 2005
It is commonly accepted that apoptosis plays an important role in the death of normal and neoplastic cells. Related proteins and their receptors on cell surfaces regulate apoptosis. One of the best-characterized systems is the Fas-Fas ligand system. The aim of the study was to examine the concentrations of soluble Fas receptor (sFas) and the soluble ...
Z, Kondera-Anasz, A, Mielczarek-Palacz, J, Sikora   +2 more
openaire   +2 more sources

Apoptosis regulated by a death factor and its receptor: Fas ligand and Fas

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1994
Abstract Homeostasis in vertebrates is tightly regulated by not only proliferation and differentiation of cells, but also cell death or apoptosis (Ellis et al. 1991; Raff 1992). Many cytokines bind to their respective receptors to regulate proliferation and differentiation of cells.
openaire   +2 more sources