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Fas receptor signaling is requisite for B cell differentiation
Journal of Leukocyte Biology, 2005AbstractThe Fas/Fas ligand (FasL) pathway has been largely implicated in the homeostasis of mature cells. However, it is still unclear whether it plays a role at the progenitor level. To address this issue, we created chimeric mice by transferring C57BL/6 bone marrow (BM) cells of the lpr (Fas−FasL+) or gld (Fas+FasL−) genotype into Rag-2−/− hosts of ...
Pasqualetto, Valérie +4 more
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Fas receptor expression on asthmatic eosinophils.
Research communications in molecular pathology and pharmacology, 1999Activation of the Fas receptor (Fas; CD95) on eosinophils induces apoptosis and may play a role in controlling eosinophil number in blood and tissue. To determine whether Fas expression on eosinophils is different between asthmatics and non-asthmatics, eosinophils were isolated from the peripheral blood using a three-step procedure of dextran ...
J E, Fahy +3 more
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Analysis of Tyr to Phe and fa/fa leptin receptor mutations in the PC12 cell line.
European cytokine network, 1999Weight regulation through body-fat content and energy homeostasis, is regulated mainly through the actions of leptin. Herein, we analyse the effect of mutations in the mouse leptin receptor using the PC12 pheochromocytoma cell line as a model system. Both the induction of pancreatitis associated protein 1 and metallothionein-II, two leptin regulated ...
Eyckerman, S +5 more
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The Fas/APO-1 receptor and its deadly ligand
Trends in Cell Biology, 1994The cell surface receptor Fas/APO-1 and its ligand have recently been identified as important mediators of apoptosis. Both molecules are crucial for the maintenance of a sound immune system, and when defective they give rise to severe autoimmune disorders.
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The Fas Receptor/Fas-Associated Protein and Cocaine
2016M. Julia García-Fuster +2 more
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[Expression of Fas receptor and soluble Fas ligand (sFasL) concentration in acute leukemia].
Polskie Archiwum Medycyny Wewnetrznej, 2003Apoptosis mediated by the interaction of cytotoxic T lymphocyte with blast cell via Fas receptor/Fas ligand (FasL) pathway is a one of the mechanisms of immunological leukemia surveillance. There is few data on possible blocking of Fas receptor by soluble form of Fas (sFasL) present in serum and the role of blast cells as the source of this ligand ...
Donata, Urbaniak-Kujda +5 more
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