Normal levels of serum corticosterone and hepatic glucocorticoid receptors in obese (fa/fa) rats
Bioscience Reports, 1987 In an attempt to understand the hyper-responsiveness to glucocorticoids that is characteristic of genetically obese fa/fa rats, we have measured the levels of free corticosterone in serum from lean and obese rats as well as the number of “cytosolic” and “nuclear” binding sites in livers of these rats. Both the lean and obese rats had similar amounts of
N S, Shargill, I, Al-Baker, D A, York
openaire +2 more sources
In vitro culture with gemcitabine augments death receptor and NKG2D ligand expression on tumour cells [PDF]
, 2019 Much effort has been made to try to understand the relationship between chemotherapeutic treatment of cancer and the immune system. Whereas much of that focus has been on the direct effect of chemotherapy drugs on immune cells and the release of antigens
A Ashkenazi +32 more
core +2 more sources
Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]
, 2020 Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P. +7 more
core +2 more sources
Az SHP1 szerepe a Fas közvetített jelátviteli folyamatokban = The role of SHP1 in Fas mediated signaling [PDF]
, 2008 Az apoptózis a sejtek elhalásának egyik legintenzívebben tanulmányozott, legjobban ismert formája. A sejthalált indukáló receptorok, köztük az általunk vizsgált Fas receptor, illetve az ezek által kiváltott jelet továbbító molekulák az apoptózis kutatás
Koncz, Gábor
core
Mice Lacking Functional Fas Death Receptors Are Protected from Kainic Acid-Induced Apoptosis in the Hippocampus [PDF]
, 2016 © 2014, Springer Science+Business Media New York. The Fas receptor (FasR)/Fas ligand (FasL) system plays a significant role in the process of neuronal loss in neurological disorders.
Camins, Antoni +3 more
core +1 more source
Modulation of Fas receptor proteins and dynamin during opiate addiction and induction of opiate withdrawal in rat brain [PDF]
, 2018 The Fas receptor is involved in the regulation of apoptosis but also can function as a non-apoptotic signal transducer. This study was mainly designed to quantitate Fas proteins in rat brain during heroin addiction and opiate withdrawal.
Ferrer-Alcón, Marcel +3 more
core
A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice. [PDF]
, 2014 It is well known that the ω-3 fatty acids (ω-3-FAs; also known as n-3 fatty acids) can exert potent anti-inflammatory effects. Commonly consumed as fish products, dietary supplements and pharmaceuticals, ω-3-FAs have a number of health benefits ascribed ...
Akiyama, Taro E +20 more
core +1 more source
Cell Death and DiseaseThe P23H variant of rhodopsin (RHO) is a common cause of autosomal dominant retinitis pigmentosa (adRP). Our previous data have shown that both the Fas (CD95) death receptor and hyperactivation of autophagy contribute to photoreceptor (PR) death in a ...
Mengling Yang +4 more
doaj +1 more source
In Vivo Localization of Fas-Associated Death Domain Protein in the Nucleus and Cytoplasm of Normal Thyroid and Liver Cells [PDF]
, 2009 FADD (Fas-associated death domain) is the main death receptor adaptor molecule that transmits apoptotic signal. Recently, FADD protein was shown to be expressed both in the cytoplasm and nucleus of in vitro cell lines. In contrast to the cytoplasmic FADD,
Chiocchia, Gilles +2 more
core +5 more sources
Alteration of Regulation of Fas/FasL Mediated Apoptosis in Gastric Cancer [PDF]
Revista Ciencias de la Salud, 2009 Gastric cancer is an important neoplasticdisease in all around the world because its highincidence and mortality. Otherwise, apoptosis isa key process of programmed cell death duringembryogenesis, regulation of immune system,and holding the tissue ...
Reggie García Robles +2 more
doaj