Results 11 to 20 of about 30,088 (148)

FasL Is Required for Osseous Healing in Extraction Sockets in Mice

Frontiers in Immunology, 2021
Fas ligand (FasL) is a member of the tumor necrosis factor (TNF) superfamily involved in the activation of apoptosis. Assuming that apoptosis is initiated after tooth extraction it is reasonable to suggest that FasL may play a pivotal role in the healing
Karol Alí Apaza Alccayhuaman, Karol Alí Apaza Alccayhuaman, Patrick Heimel, Patrick Heimel, Patrick Heimel, Jung-Seok Lee, Jung-Seok Lee, Stefan Tangl, Stefan Tangl, Franz J. Strauss, Franz J. Strauss, Franz J. Strauss, Alexandra Stähli, Eva Matalová, Reinhard Gruber, Reinhard Gruber, Reinhard Gruber   +16 more
doaj   +1 more source

Species difference in the expression of Fas and Fas ligand in mature mammalian spermatozoa

Czech Journal of Animal Science, 2017
Although it has been proposed that the Fas and Fas ligand (FasL) may protect ejaculated spermatozoa against apoptosis induced by lipoperoxidative damage and against lymphocytes present in the female genital tract, studies reported conflicting results on ...
Youwei Li, Mingju Sun, Jiang Zhu, Guangzhong Jiao, Juan Lin, Haibo Dong, Jinghe Tan, Jiabo Zhou   +7 more
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A connection between levels of soluble Fas and Fas ligand in the aqueous humor and the parameters of structural and functional damage of glaucoma patients [PDF]

Srpski Arhiv za Celokupno Lekarstvo
Introduction/Objective Fas ligand (FasL) induces apoptosis when interacting with the Fas-receptor. The aim was to determine the concentration of soluble Fas (sFas) and soluble FasL (sFasL) in the aqueous humor (AH) of open-angle glaucoma patients, and ...
Trenkić Marija, Jevtović-Stoimenov Tatjana, Bašić Jelena, Stamenković Miroslav, Jocić-Đorđević Jasmina, Trenkić Milan   +5 more
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The role of apoptosis in pathogenesis of type 1 diabetes mellitus

Сахарный диабет, 2010
Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess.
Elena Vladimirovna Pekareva, Tatiana Vasil'evna Nikonova, Olga Mikhailovna Smirnova   +2 more
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Enhanced expression of Fas Ligand (FasL) in the lower airways of patients with fibrotic interstitial lung diseases (ILDs)

Folia Histochemica et Cytobiologica, 2012
The exact role of FasL, and particularly its soluble and membrane-bound forms, in the development of chronic ILDs and lung fibrosis has not been extensively explored.
Teresa Iwaniec, Marek Jankowski, Tomasz Wandtke, Agnieszka Jarzemska, Grzegorz Przybylski, Adam Szpechciński, Andrzej Dyczek, Barbara Balicka-Ślusarczyk, Piotr Kopiński, Joanna Chorostowska-Wynimko   +9 more
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Modulation of CD8+ memory stem T cell activity and glycogen synthase kinase 3β inhibition enhances anti-tumoral immunity in gastric cancer

OncoImmunology, 2018
The potential contributions of CD8+ memory stem T cells to anti-tumor immunity and immunotherapy responses in gastric cancer has not been demonstrated.
Jin-yu Zhang, Yong-liang Zhao, Yi-pin Lv, Ping Cheng, Weisan Chen, Mubin Duan, Yong-sheng Teng, Ting-ting Wang, Liu-sheng Peng, Fang-yuan Mao, Yu-gang Liu, Xiao-long Fu, Pei-wu Yu, Ping Luo, Wei-jun Zhang, Quan-ming Zou, Yuan Zhuang   +16 more
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Mechanism of nuclear factor of activated T-cells mediated FasL expression in corticosterone -treated mouse Leydig tumor cells

BMC Cell Biology, 2008
Background Fas and FasL is important mediators of apoptosis. We have previously reported that the stress levels of corticosterone (CORT, glucocorticoid in rat) increase expression of Fas/FasL and activate Fas/FasL signal pathway in rat Leydig cells ...
Wang Qian, Chen Yong, Chai Wei-Ran, Gao Hui-Bao   +3 more
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Fas/FasL Signaling Regulates CD8 Expression During Exposure to Self-Antigens

Frontiers in Immunology, 2021
Activation of self-reactive CD8+ T cells induces a peripheral tolerance mechanism that involves loss of CD8 expression. Because genetic deficiency of Fas and Fasl causes the accumulation of double-negative (DN; CD3+ TCR-αβ+ CD4- CD8-) T cells that have ...
Giovanna Flores-Mendoza, Giovanna Flores-Mendoza, Noé Rodríguez-Rodríguez, Rosa M. Rubio, Iris K. Madera-Salcedo, Florencia Rosetti, José C. Crispín, José C. Crispín   +7 more
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Soluble Fas Ligand Is Essential for Blister Formation in Pemphigus

Frontiers in Immunology, 2018
Pemphigus is a blistering disease characterized by pemphigus autoantibodies (PVIgG) directed mostly against desmogleins (Dsgs), resulting in the loss of keratinocyte adhesion (acantholysis).
Roberta Lotti, En Shu, Tiziana Petrachi, Alessandra Marconi, Elisabetta Palazzo, Marika Quadri, Ann Lin, Lorraine A. O’Reilly, Lorraine A. O’Reilly, Carlo Pincelli   +9 more
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Impact of FasL Stimulation on Sclerostin Expression and Osteogenic Profile in IDG-SW3 Osteocytes

Biology, 2021
The Fas ligand (FasL) is known from programmed cell death, the immune system, and recently also from bone homeostasis. As such, Fas signalling is a potential target of anti-osteoporotic treatment based on the induction of osteoclastic cell death.
Adela Kratochvilova, Alice Ramesova, Barbora Vesela, Eva Svandova, Herve Lesot, Reinhard Gruber, Eva Matalova   +6 more
doaj   +1 more source