Results 41 to 50 of about 797,546 (295)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Fast ion studies in the extended high-performance high βP plasma on EAST
Comprehending and optimizing fast ion behaviors is critical for the enhancement of performance in Experimental Advanced Superconducting Tokamak (EAST).
Y.X. Sun +19 more
doaj +1 more source
Deterministic entanglement of ions in thermal states of motion
We give a detailed description of the implementation of a Molmer-Sorensen gate entangling two Ca+ ions using a bichromatic laser beam near-resonant with a quadrupole transition.
Abramowitz M +10 more
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
New approach to highly accurate calculations of the photodetachment cross-sections of the negatively charged hydrogen ions is developed. This effective, fast and numerically stable method is based on the use of the Rayleigh's formula for the spherical ...
Frolov, Alexei M.
core +1 more source
Fast ion conductors with rotating sulphate ions
X-ray and neutron diffraction studies of fcc Li2SO4 (575 to 860 °C for pure Li2SO4) show a high degree of spherical delocation of the sulphate ions. This strongly coupled rotation causes the dimensions of the cation positions to be varying all the time.
Aronsson, R. +6 more
openaire +2 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Orbit simulations of fast-ion transport induced by externally applied 3D magnetic perturbations in the ASDEX Upgrade tokamak. [PDF]
Externally applied 3D magnetic perturbations break the symmetry of the magnetic field in a tokamak and have an impact on the transport of fast-ions, i.e. suprathermal ions.
González Rosa, Jesús
core
Negative-ion neutral-beam injection (NNBI) is an important source of heating and current drive for next-step fusion devices where the injected energy can range from hundreds of keV to 1 MeV. Few diagnostics are suitable for phase-space resolved measurements of fast ions with energy in excess of 100 keV.
C. M. Muscatello +6 more
openaire +3 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source

