Circadian PER1 controls daily fat absorption with the regulation of PER1-PKA on phosphorylation of bile acid synthetase [PDF]
Journal of Lipid Research, 2023 Several epidemiological studies suggest a correlation between eating time and obesity. Night eating syndrome characterized by a time-delayed eating pattern is positively associated with obesity in humans as well as in experimental animals.
Wenhao Ge +5 more
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Intestinal Reg4 deficiency confers susceptibility to high-fat diet-induced liver steatosis by increasing intestinal fat absorption in mice [PDF]
JHEP Reports, 2023 Background & Aims: Regenerating gene family member 4 (REG4) is a novel marker for enteroendocrine cells and is selectively expressed in specialised enteroendocrine cells of the small intestine. However, the exact roles of REG4 are largely unknown. In
Ying Wang +9 more
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Chronic high-fat diet feeding reduces the rate of postprandial triglyceride absorption independent of intestinal ANGPTL4 [PDF]
Journal of Lipid ResearchPancreatic lipase is the major enzyme responsible for breaking down dietary triglycerides in the intestines. A previous report suggested that intestinal angiopoietin-like 4 (ANGPTL4) might serve as an endogenous inhibitor of pancreatic lipase and thus ...
Shwetha K. Shetty +2 more
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Stress-induced Regulators of Intestinal Fat Absorption [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2022 Kezhong Zhang, PhD
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Editorial: Advances in Dietary Fat Absorption [PDF]
Frontiers in Physiology, 2021 Andromeda M. Nauli +2 more
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GPR182 is a lipoprotein receptor for dietary fat absorption [PDF]
The Journal of Clinical InvestigationThe lymphatic system plays a central role in lipid absorption by transporting triglyceride-rich particles called chylomicrons (CMs) from the small intestine to the systemic circulation.
Zhiwei Sun +20 more
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Platycodon D reduces obesity and non-alcoholic fatty liver disease induced by a high-fat diet through inhibiting intestinal fat absorption [PDF]
Frontiers in PharmacologyBackgroundPlatycodin D (PD) has been reported to treat metabolic diseases, including non-alcoholic fatty liver disease. In addition, platycodin D has been reported to activate intestinal 5'AMP-activated protein kinase (AMPK) phosphorylation levels ...
Xingkui Tang +10 more
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Monoglyceride modification of jejunal absorption of fatty acid in the rat
Journal of Lipid Research, 1974 The effect of increasing the intracellular pool of monoolein upon the subsequent uptake and esterification of oleic acid was investigated using in vitro rat jejunal slice techniques.
A. Thomas Marubbio, Jr. +3 more
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Protein Kinase D2 drives chylomicron‐mediated lipid transport in the intestine and promotes obesity
EMBO Molecular Medicine, 2021 Lipids are the most energy‐dense components of the diet, and their overconsumption promotes obesity and diabetes. Dietary fat content has been linked to the lipid processing activity by the intestine and its overall capacity to absorb triglycerides (TG).
Jonathan Trujillo‐Viera +23 more
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Frontiers in Sustainable Food Systems, 2023 The present study evaluated the impact of carob-based coating films on Fat %, moisture %, fat uptake %, moisture retention %, and sensory scores of Kubeh during deep-fat frying.
Malak Angor
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