Results 191 to 200 of about 177,365 (251)

Global GPR75 deficiency protects against diet-induced obesity through central and peripheral mechanisms. [PDF]

Mol Metab
Cao X, Chhay V, Thi TT, Li H, Shi Y, Wang Y, Min Y, Song R, Cheng KY, Yang Y, Jong-Leong Wong J, Yu H.   +11 more
europepmc   +1 more source

SIRT5‐Mediated Desuccinylation of ACAA2 Protects Against Calcium Oxalate‐Induced Kidney Injury by Regulating Fatty Acid Oxidation to Suppress Mitochondrial Oxidative Injury and Ferroptosis

Advanced Science, EarlyView.
The SIRT5/ACAA2 axis maintains lipid metabolic homeostasis in RTECs by promoting ACAA2 desuccinylation and preserving its stability and enzymatic activity, thereby sustaining FAO and limiting PUFA and PUFA‐containing phospholipid accumulation. Under CaOx stress, SIRT5 downregulation impairs FAO, promotes oxidative stress and ferroptosis, and enhances ...
Qinhong Jiang, Caitao Dong, Yuchen Liu, Yuanquan Lou, Wenlong Lin, Sheng Li, Ziqi He   +6 more
wiley   +1 more source

Physiologically Based Pharmacokinetic Modeling of Venetoclax in Pediatric Acute Myeloid Leukemia: Food Effects, Age-Related Pharmacokinetics, and Voriconazole-Mediated Drug-Drug Interactions. [PDF]

Pharmaceutics
Li Y, Liu M, Ling Q, Sun N, Zheng H, Guo P, Zhao L.   +6 more
europepmc   +1 more source

Intestinal fructose catabolism promotes obesity and insulin resistance via ileal lacteal remodeling. [PDF]

Sci Adv
Lopez ML, Kang T, Espeleta AM, Rubtsova VI, Baek J, Songcuan J, Moyer EM, Kim J, Song WS, Jung S, Lai RW, Binuya A, Lee CH, Lantz AR, D'Sa N, Anica A, Tran E, Chun Y, Choi W, Jang KH, Cho S, Kelly ME, Tamburini IJ, Alam YH, Le J, Ramirez CB, Kataru RP, Hong SP, de Aguiar Vallim TQ, Nicholas DA, Xue KS, Lee G, Bae H, Jang C.   +33 more
europepmc   +1 more source

A Review on Parrot Gut Health: Insights into the Intestinal Structure, Microbiota Diversity, Influencing Factors, and Nutritional Strategies. [PDF]

Vet Sci
Jia Y, Li Y, Shaukat A, Huang SC.
europepmc   +1 more source

Beyond Saturated Fat: A Four-Dimensional Framework for Understanding Milk Fat in Human Health. [PDF]

Compr Rev Food Sci Food Saf
Liu N, Duan S, He J, Feng G, Deng Z, Li J.   +5 more
europepmc   +1 more source

Development and nutritional evaluation of an extruded grain amaranth-instant porridge as a supplementary food for children under five with moderate acute malnutrition. [PDF]

Front Nutr
Mwikwabe AS, Martin HD, Mushi BK, Kejo DD.   +3 more
europepmc   +1 more source