Results 221 to 230 of about 696,395 (294)

Design, Synthesis, and Biological Evaluation of Pyrazolyl Thioureas (PTUs) as SIRT1 and SIRT2 Inhibitors

open access: yesChemMedChem, Volume 21, Issue 18, 28 September 2026.
Pyrazolyl thioureas were designed and synthesized as sirtuin 1 (SIRT1) and sirtuin 2 (SIRT2) inhibitors. 6a (IC50 (SIRT1) = 5.3 µM; IC50 (SIRT2) = 2.2 µM) and 7f (IC50 (SIRT1) = 12.4 µM; IC50 (SIRT2) = 13.6 µM) showed micromolar inhibition on target enzymes and HepG2‐based assays confirmed a SIRT2‐mediated effect on tubulin acetylation. Docking studies
Matteo Lusardi   +10 more
wiley   +1 more source

Biobased Oligo‐ and Polyesters from Fatty Acids with Demonstrated Biodegradability or Recyclability for Industrial Applications in a Circular Economy

open access: yesChemSusChem, Volume 19, Issue 17, 14 September 2026.
This “Perspectives”‐article describes and discusses two recent developments in the field of biobased as well as biodegradable or chemically recyclable oligomers/polymers for applications in the lubricant and plastics product segments, which are efficiently accessible and which are based on the utilization of unsaturated fatty acids as feedstocks. This “
Harald Gröger
wiley   +1 more source

Synthesis and Functional Properties of Fluorinated Phosphonate‐Substituted Porphyrins: Excellent Photosensitizers and Robust Precursors for Photoactive Langmuir–Schaefer Films

open access: yesChemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
This is a comprehensive study of new family of high functionalized meso‐tetraarylporphyrins. A synthetic approach to phosphonate‐substituted fluorinated porphyrins was developed. These compounds were investigated with respect to singlet oxygen generation and photostability.
Azhar Kechiche   +8 more
wiley   +1 more source

Enhancing Efficiency and Stability of Perovskite Solar Cells Through Electron-Rich Covalent Organic Frameworks Radicals. [PDF]

open access: yesAngew Chem Int Ed Engl
Yang S   +10 more
europepmc   +1 more source

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