Results 31 to 40 of about 146,490 (301)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Conserved function of the long noncoding RNA Blnc1 in brown adipocyte differentiation

Molecular Metabolism, 2017
Objective: Long noncoding RNAs (lncRNAs) are emerging as important regulators of diverse biological processes. Recent work has demonstrated that the inducible lncRNA Blnc1 stimulates thermogenic gene expression during brown and beige adipocyte ...
Lin Mi, Xu-Yun Zhao, Siming Li, Gongshe Yang, Jiandie D. Lin   +4 more
doaj   +1 more source

Ectopic Fat Deposition and Diabetes Mellitus

Journal of the American College of Cardiology, 2016
Dr. Zhu and colleagues also note the different situations in which the vasovagal reflex can occur, and suggest matching work and life environments between the placebo and fludrocortisone groups. Although an interesting and insightful comment, this might not be practical.
Gaborit, Benedicte, Dutour, Anne
openaire   +3 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Peripheral Neuropathy and Hindlimb Paralysis in a Mouse Model of Adipocyte-Specific Knockout of Lkb1

EBioMedicine, 2017
Brown adipose tissues (BAT) burn lipids to generate heat through uncoupled respiration, thus representing a powerful target to counteract lipid accumulation and obesity.
Yan Xiong, Jessica C. Page, Naagarajan Narayanan, Chao Wang, Zhihao Jia, Feng Yue, Xine Shi, Wen Jin, Keping Hu, Meng Deng, Riyi Shi, Tizhong Shan, Gongshe Yang, Shihuan Kuang   +13 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Integrating parental genomes to reduce reference bias and identify intramuscular fat genes in Qinchuan Black pigs

Journal of Animal Science and Biotechnology
Background Traditional genomic analysis relies on a single reference genome, which struggles to effectively characterize the genetic diversity among populations. This is due to the substantial genetic differences between the genome of the studied species
Guangquan Lv, Peiyu Yang, Ao Guo, Minghao Cao, Dong Li, Zhe Liu, Mingyu Wang, Jingchun Sun, Rongrong Ding, Taiyong Yu   +9 more
doaj   +1 more source

Identification of TRAPPC9 and BAIAP2 Gene Polymorphisms and Their Association With Fat Deposition-Related Traits in Hu Sheep

Frontiers in Veterinary Science, 2022
Fat deposition is an important economic trait that is closely related to feed efficiency and carcass performance in livestock. In this study, the fat deposition-related traits of 1,293 Hu sheep were measured and descriptive statistical analysis was ...
Panpan Cui, Weimin Wang, Weimin Wang, Deyin Zhang, Chong Li, Yongliang Huang, Zongwu Ma, Xiaojuan Wang, Liming Zhao, Yukun Zhang, Xiaobin Yang, Dan Xu, Jiangbo Cheng, Xiaolong Li, Xiwen Zeng, Yuan Zhao, Wenxin Li, Jianghui Wang, Changchun Lin, Bubo Zhou, Jia Liu, Rui Zhai, Xiaoxue Zhang   +22 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Patterns of carcass fat deposition in heifers, steers and bulls

, 1979
Seventy-five young, full-fed, Shorthorn-sired cattle (36 heifers, 24 steers, 15 bulls) were slaughtered over a wide liveweight range (150-550 kg) to evaluate the influence of sex on the patterns of fat ...
Hardin, R. T., Butterfield, R. M., Price, M. A., Berg, R. T., Fukuhara, R., Jones, S. D. M.   +5 more
core   +1 more source