Results 91 to 100 of about 6,179,891 (361)

Fatty acid oxidation and carnitine palmitoyltransferase I: emerging therapeutic targets in cancer

Cell Death and Disease, 2016
Tumor cells exhibit unique metabolic adaptations that are increasingly viewed as potential targets for novel and specific cancer therapies. Among these targets, the carnitine palmitoyltransferase system is responsible for delivering the long-chain fatty ...
Q. Qu, F. Zeng, Xiaoju Liu, Q. Wang, Feihong Deng   +4 more
semanticscholar   +1 more source

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

FEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey, Lina Riegler‐Berket, Monika Oberer   +2 more
wiley   +1 more source

Impact of sustainable feeds on omega-3 long-chain fatty acid levels in farmed Atlantic salmon, 2006–2015

Scientific Reports, 2016
As the global population and its demand for seafood increases more of our fish will come from aquaculture. Farmed Atlantic salmon are a global commodity and, as an oily fish, contain a rich source of the health promoting long-chain omega-3 fatty acids ...
M. Sprague, J. Dick, D. Tocher
semanticscholar   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Dietary alterations of fatty acids of erythrocytes and mitochondria of brain and liver*

Journal of Lipid Research, 1961
The fatty acid composition of erythrocyte and liver mitochondrial lipids was readily and drastically altered by varying the fatty acid content of the diet.
L.A. Witting, C.C. Harvey, B. Century, M.K. Horwitt   +3 more
doaj   +1 more source

Dose-Response Effect of Elevated Plasma Free Fatty Acid on Insulin Signaling [PDF]

, 2005
Renata Belfort, Lawrence J. Mandarino, Sangeeta Kashyap, Kelly L. Wirfel, Thongchai Pratipanawatr, Rachele Berria, Ralph A. DeFronzo, Kenneth Cusi   +7 more
openalex   +1 more source

Multidimensional trophic niche revealed by complementary approaches: Gut content, digestive enzymes, fatty acids and stable isotopes in Collembola

, 2021
Anton Potapov, Melanie M. Pollierer, Sandrine Salmon, Vladimír Šustr, Ting‐Wen Chen   +4 more
openalex   +1 more source

Fatty acid synthesis is required for breast cancer brain metastasis

Nature Cancer, 2021
G. Ferraro, A. Ali, Alba Luengo, David P. Kodack, A. Deik, Keene L. Abbott, Divya Bezwada, L. Blanc, Brendan Prideaux, Xin Jin, Jessica M Posada, Jiang Chen, Christopher R Chin, Zohreh Amoozgar, Raphael Ferreira, Ivy X. Chen, K. Naxerova, C. Ng, Anna M. Westermark, M. Duquette, S. Roberge, N. Lindeman, C. Lyssiotis, J. Nielsen, D. Housman, D. Duda, E. Brachtel, T. Golub, L. Cantley, J. Asara, S. Davidson, D. Fukumura, V. Dartois, C. Clish, R. Jain, M. V. Vander Heiden   +35 more
semanticscholar   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Tween 80™-induced changes in fatty acid profile of selected mesophilic lactobacilli

Acta Biochimica Polonica
Fatty acid profiles are crucial for the functionality and viability of lactobacilli used in food applications. Tween 80™, a common culture media additive, is known to influence bacterial growth and composition.
Dorota Zaręba, Małgorzata Ziarno
doaj   +1 more source