Results 71 to 80 of about 3,736,253 (314)

Partition of fatty acids

Journal of Lipid Research, 1974
The partition ratios of radioactive fatty acids between n-heptane and a physiological buffer at 37 degrees C were measured. The fatty acids included the saturated acids with an even number of carbons from 10 to 18 and the unsaturated acids oleic, linoleic, and linolenic.
Richard B. Simpson, J. Douglas Ashbrook, Elsa C. Santos, Arthur A. Spector   +3 more
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Pre-pregnancy overweight or obesity moderates the association between prenatal maternal depressive symptoms and infant cord blood omega-3 levels

BMC Pregnancy and Childbirth
Background Empirical evidence has demonstrated associations between pre-pregnancy obesity and perinatal maternal depressive symptoms. Omega-3 is an essential fatty acid derived from dietary sources that is critical for fetal brain development.
Lauren A. Costello, Katherine Ziegler, Lacey McCormack, Anahid Akbaryan, Julianna Collazo Vargas, William S. Harris, Kristina H. Jackson, Maria Barber, Santiago Morales, Amy J. Elliott, Christine Hockett, Lauren C. Shuffrey   +11 more
doaj   +1 more source

Utilization of free fatty acids complexed to human plasma lipoproteins by mammalian cell suspensions

Journal of Lipid Research, 1971
The purpose of this study was to determine whether lipoprotein-bound free fatty acid could be utilized by isolated mammalian cells. Ehrlich ascites tumor cells were incubated in vitro with radioactive free fatty acids that were bound to human plasma ...
ARTHUR A. SPECTOR, JANICE M. SOBOROFF
doaj   +1 more source

Induction of lipid oxidation by polyunsaturated fatty acids of marine origin in small intestine of mice fed a high-fat diet [PDF]

, 2009
Background. Dietary polyunsaturated fatty acids (PUFA), in particular the long chain marine fatty acids docosahexaenoic (DHA) and eicosapentaenoic (EPA), are linked to many health benefits in humans and in animal models.
Schothorst, E.M., van, Evert M van Schothorst, Annelies Bunschoten, Jaap Keijer, Molthoff, J.W., Keijer, J., Flachs, P., Bunschoten, A., Kopecky, J., Vink, C., Franssen-Hal, N.L.W., van, Ondrej Kuda, Carolien Vink, Nicole LW Franssen-van Hal, Guido JEJ Hooiveld, Pavel Flachs, Kuda, O., Hooiveld, G.J.E.J., Jan Kopecky, Jos Molthoff   +19 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Sexually dimorphic brain fatty acid composition in low and high fat diet-fed mice

Molecular Metabolism, 2016
Objective: In this study, we analyzed the fatty acid profile of brains and plasma from male and female mice fed chow or a western-style high fat diet (WD) for 16 weeks to determine if males and females process fatty acids differently.
Carlos Rodriguez-Navas, Eugenia Morselli, Deborah J. Clegg   +2 more
doaj   +1 more source

Is There a Fatty Acid Taste? [PDF]

Annual Review of Nutrition, 2009
Taste is a chemical sense that aids in the detection of nutrients and guides food choice. A limited number of primary qualities comprise taste. Accumulating evidence has raised a question about whether fat should be among them. Most evidence indicates triacylglycerol is not an effective taste stimulus, though it clearly contributes sensory properties ...
openaire   +2 more sources

Essential fatty acids and their long-chain polyunsaturated metabolites in maternal and cord plasma triglycerides during late gestation [PDF]

, 2000
The fatty acid composition of plasma lipids was determined in 41 pairs of mothers and their term infants at time of birth (38-42 postmenstrual weeks) by high-resolution capillary gas-liquid chromatography, Linoleic and alpha-linolenic acids were found at
Koletzko, Berthold, Berghaus, Thomas M., Demmelmair, Hans   +2 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source