Results 121 to 130 of about 3,736,253 (314)

Relationship between Polyunsaturated Fatty Acid Metabolism and Atherosclerosis

Reviews in Cardiovascular Medicine
Multiple factors cause atherosclerosis, meaning its pathogenesis is complex, and has not been fully elucidated. Polyunsaturated fatty acids are a member of the fatty acid family, which are critical nutrients for mammalian growth and development.
Qiulei Liu, Zhaoxuan Liu, Ding Wu, Sheng Wang   +3 more
doaj   +1 more source

Unsaturated fatty acids [PDF]

Proceedings of the Nutrition Society, 1999
There is good scientific evidence that dietary fatty acid composition is involved in the aetiology of many diseases. Increasing the supply of n−3 polyunsaturated fatty acids (PUFA) may reduce the risk of CHD. Several scientific organizations (for example, see Department of Health, 1991, 1994; British Nutrition Foundation, 1992; Scientific Committee for
openaire   +2 more sources

Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis

, 2012
Nutrition during development affects risk of future cardiovascular disease. Relatively little is known about whether the amount and type of fat in the maternal diet affect vascular function in the offspring.
Masoodi, Mojgan, Geraldine F Clough, Karen A Lillycrop, Samuel P Hoile, Karen A. Lillycrop, Irvine, Nicola A., Philip C. Calder, Graham C. Burdge, Kelsall, Christopher J., Christopher Torrens (114420), Geraldine F. Clough, Geraldine F. Clough (114433), Christopher J. Kelsall, Lillycrop, Karen A., Calder, Philip C., Mojgan Masoodi (152735), Mark A. Hanson (114427), Hoile, Samuel P., Burdge, Graham C., Christopher J. Kelsall (173702), Mark A Hanson, Christopher J Kelsall, Graham C Burdge, Nicola A. Irvine (173711), Torrens, Christopher, Samuel P. Hoile, Nicola A Irvine, Graham C. Burdge (173729), Philip C Calder, Mojgan Masoodi, Hanson, Mark A., Philip C. Calder (173723), Christopher Torrens, Nicola A. Irvine, Clough, Geraldine F., Mark A. Hanson, Samuel P. Hoile (173705), Karen A. Lillycrop (173718)   +37 more
core   +1 more source

Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress [PDF]

, 2010
Although dietary fatty acids are a major fuel for the heart, little is known about the direct effects of dietary fatty acids on gene regulation in the intact ...
Degenhardt, Tatjana, Boekschoten, M.V., Kersten, A.H., Boekschoten, Mark V., Georgiadi, Anastasia, Lichtenstein, Laeticia, Müller, Michael, Georgiadi, A., Bilsen, M., van, van Bilsen, Marc, Müller, M.R., Lichtenstein, L.L., Desvergne, Beatrice, Degenhardt, T., Desvergne, B., Boekschoten, Mark V, van Bilsen, M., Kersten, Sander, Kersten, S., Müller, M., Lichtenstein, L.   +20 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Tween 80™-induced changes in fatty acid profile of selected mesophilic lactobacilli

Acta Biochimica Polonica
Fatty acid profiles are crucial for the functionality and viability of lactobacilli used in food applications. Tween 80™, a common culture media additive, is known to influence bacterial growth and composition.
Dorota Zaręba, Małgorzata Ziarno
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source