Results 101 to 110 of about 1,543,666 (403)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Inferring phytoplankton community composition with a fatty acid mixing model

open access: yes, 2015
The taxon specificity of fatty acid composition in algal classes suggests that fatty acids could be used as chemotaxonomic markers for phytoplankton composition.
U. Strandberg   +5 more
semanticscholar   +1 more source

An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity

open access: yesNutrients, 2016
In the past three decades, total fat and saturated fat intake as a percentage of total calories has continuously decreased in Western diets, while the intake of omega-6 fatty acid increased and the omega-3 fatty acid decreased, resulting in a large ...
A. Simopoulos
semanticscholar   +1 more source

Organic vs Conventional Suckling Lamb Production: Product Quality and Consumer Acceptance [PDF]

open access: yes, 2008
Samples of suckling lambs (n=40) of two breeds reared under conventional and organic conditions were analysed to asses physico-chemical characteristics, including instrumental texture, and nutritional quality in terms of fatty acid composition.
Lurueña-Martínez, M.A.   +4 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Sexually dimorphic brain fatty acid composition in low and high fat diet-fed mice

open access: yesMolecular Metabolism, 2016
Objective: In this study, we analyzed the fatty acid profile of brains and plasma from male and female mice fed chow or a western-style high fat diet (WD) for 16 weeks to determine if males and females process fatty acids differently.
Carlos Rodriguez-Navas   +2 more
doaj   +1 more source

Fatty acid composition of Piedmont “Ossolano” cheese [PDF]

open access: yesLe Lait, 2003
Composition en acides gras du fromage " Ossolano " du Piémont. La composition en acides gras a été déterminée dans 66 échantillons d'" Ossolano ", un fromage à pâte semi-dure qui est produit à partir du lait cru dans la vallée de l'Ossola (Piémont du Nord, Italie). Vingt-quatre de ces fromages ont été fabriqués en été à partir de laits produits sur des
ZEPPA, Giuseppe   +3 more
openaire   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

The fatty acid composition of brain sphingolipids: sphingomyelin, ceramide, cerebroside, and cerebroside sulfate

open access: yesJournal of Lipid Research, 1964
Sphingomyelin, ceramide, cerebroside, and cerebroside sulfate from beef brain were isolated by column chromatography in quantitative yield and in pure form. The fatty acid composition of each sphingolipid was determined by gas-liquid chromatography (GLC).
John S. O'Brien, George Rouser
doaj   +1 more source

Mathematical Development Program for Calculation of Fatty Acid Composition Blend of Vegetable Oils [PDF]

open access: yes, 2016
The method of solution of the problem of polyunsaturated fatty acids (PUFA) lack in milk products is offered in the work. It is offered to create the milk-containing products (sour cream product) with adjusted fatty acid composition.
Belemets, T. (Tatiana)   +4 more
core   +2 more sources

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