Results 201 to 210 of about 39,848 (282)

Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou, Sheng He, Lili He, Kun Liu, Wen Tang, Deming Wang, Jing Gui, Zhiying Zeng, Yan Wang, Wenjie Liu, Ren Jing   +10 more
wiley   +1 more source

Divergent fatty acid desaturase 2 is essential for falcarindiol biosynthesis in carrot. [PDF]

Plant Commun
Zhu J, Ahmad N, Zhou X, He W, Wang J, Shan C, Chen Z, Ji W, Liu Z.   +8 more
europepmc   +1 more source

NSCLC Cells Resistance to PI3K/mTOR Inhibitors Is Mediated by Delta-6 Fatty Acid Desaturase (FADS2). [PDF]

Cells, 2022
Colombo M, Passarelli F, Corsetto PA, Rizzo AM, Marabese M, De Simone G, Pastorelli R, Broggini M, Brunelli L, Caiola E.   +9 more
europepmc   +1 more source

Stearoyl‐CoA Desaturase‐1 Drives Tumor Growth by Interacting With Histone Deacetylase‐2 and Deacetylating Nucleophosmin‐1

MedComm, Volume 7, Issue 6, June 2026.
Hypoxia induces SCD1 and PLIN2 to drive lipid droplet‐dependent metabolic adaptation in cancer cells. PLIN2 supports survival under stress, whereas SCD1 promotes proliferation upon reoxygenation and remodels the acetylome via HDAC2‐mediated NPM1 deacetylation and destabilization.
Coline Wery, Laetitia Montero‐Ruiz, Eric Bonneil, Mohammad Farran, Robin Jehay, Quentin Herrara Garfia, Gregory Fettweis, Silvia Blacher, Charles Pottier, Gael Cobraiville, Yasmine Boumahd, Olivier Peulen, Agnès Noël, Franck Dequiedt, Marianne Fillet, Nor Eddine Sounni   +15 more
wiley   +1 more source

Metabolic landscape uncovers remodeling of T cell immunity affected by fatty acid desaturase in Parkinson's disease at single-cell resolution. [PDF]

BMC Biol
Yan S, Zhao X, Si Y, Zhang X, Wang D, Yao L, Sun L.   +6 more
europepmc   +1 more source

Genome-Wide Identification and Expression Analysis of Fatty Acid Desaturase (FAD) Genes in Camelina sativa (L.) Crantz. [PDF]

Int J Mol Sci, 2022
Sun D, Quan W, Wang D, Cui J, Wang T, Lin M, Wang Y, Wang N, Dong Y, Li X, Liu W, Wang F.   +11 more
europepmc   +1 more source

Does Gum Arabic Alter Gene Expression? Diabetic and Obesity as Models: A Mini Review

Modern Agriculture, Volume 4, Issue 1, June 2026.
Gum Arabic (GA) modulates obesity‐ and diabetes‐related gene expression, reducing pro‐inflammatory cytokines (IL‐6, TNF‐α, IL‐1β) and increasing IL‐10. GA elevates pAMPK, pACC, and GLP‐1 while decreasing FASN and leptin, indicating improved energy and lipid metabolism. Oxidative stress markers (SOD, GPx, CAT) rise with GA, alongside increased GLUT3 and
Saber Y. Adam, Taha Hussein Musa, Hassan Hussein Musa, Ahmed A. Saleh, Abdelkareem A. Ahmed   +4 more
wiley   +1 more source

Fatty acid desaturase 3 (FADS3) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Fatty Acid Desaturase 1 Knockdown Promotes Wound Healing and Functional Recovery of the Corneal Epithelium in Diabetes. [PDF]

Invest Ophthalmol Vis Sci
Zhao Y, Dong Y, Zheng Q, Zhao Y, Ni Y, Qiu P, Chen C, Xu M, Hong C, Shen T.   +9 more
europepmc   +1 more source

Dysregulated Lipid Metabolism in Hepatocellular Carcinoma: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Dysregulated lipid metabolism facilitates hepatocellular carcinoma (HCC) development, progression, immunosuppressive tumor microenvironment (TME) formation, and therapeutic resistance. Notably, the patterns of lipid metabolism vary significantly among different types of HCC driven by various etiologies.
Yi Yi, Xi Liu, Xi Zhang, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source