Results 201 to 210 of about 633,143 (229)
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International Journal of Molecular Sciences, 2023
Colorectal cancer (CRC) cells show some alterations in lipid metabolism, including an increased fatty acid elongation. This study was focused on investigating the effect of a small interfering RNA (siRNA)-mediated decrease in fatty acid elongation on CRC
A. Czumaj +4 more
semanticscholar +1 more source
Colorectal cancer (CRC) cells show some alterations in lipid metabolism, including an increased fatty acid elongation. This study was focused on investigating the effect of a small interfering RNA (siRNA)-mediated decrease in fatty acid elongation on CRC
A. Czumaj +4 more
semanticscholar +1 more source
Lipids, 2017 Production of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in plant seed oils has been pursued to improve availability of these omega-3 fatty acids that provide important human health benefits.
Carl André, Sten Stymne
exaly +2 more sources
New understandings of the pathway of long-chain polyunsaturated fatty acid biosynthesis
Current opinion in clinical nutrition and metabolic care, 2021Purpose of review Molecular studies have clarified the roles of the fatty acid desaturase (FADSx) and elongation of very long chain fatty acid (ELOVLx) genes, as well as acyl-coenzyme A synthase long-chain isoforms (ACSLx) required for entry to long ...
J. Brenna, K. Kothapalli
semanticscholar +1 more source
Environmental Microbiology, 2022
Very long-chain fatty acids (VLCFAs), the precursors for the synthesis of sphingolipids (SLs), play pivotal roles in the development and stress response in eukaryotes.
Haixia Wang +4 more
semanticscholar +1 more source
Very long-chain fatty acids (VLCFAs), the precursors for the synthesis of sphingolipids (SLs), play pivotal roles in the development and stress response in eukaryotes.
Haixia Wang +4 more
semanticscholar +1 more source
Characterization of fatty acid elongase enzymes from germinating pea seeds
Phytochemistry, 1998In vitro biosynthesis of radioactive arachidate and behenate was observed when microsomal fractions of germinating pea seeds were incubated with exogenous stearoyl-CoA (18:0-CoA) or arachidoyl-CA (20:0-CoA) in the presence of NADPH, [2-14C]malonyl-CoA and ATP.
P B, Barrett, J L, Harwood
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The fatty acid elongase gene family in the brown planthopper, Nilaparvata lugens
Insect Biochemistry and Molecular Biology, 2019The cuticular hydrocarbon (CHC) biosynthetic pathways branches off from the synthesis of fatty acids. Fatty acid elongases (ELOs) are enzymes catalyzing the synthesis of long-chain fatty acids and thereby contribute to the diversification of CHCs. Based on bioinformatics analyses we identified 20 ELO genes in the brown planthopper, Nilaparvata lugens ...
Dan-Ting, Li +4 more
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A fatty acid elongase ELO with novel activity from Dictyostelium discoideum
Biochemical and Biophysical Research Communications, 2008Fatty acid elongation was examined in the cellular slime mold, Dictyostelium discoideum. Profiling of the total fatty acid content of D. discoideum indicated that fatty acid elongation is active. Orthologs of the fatty acid elongase ELO family were identified in the D.
Brenda J, Blacklock +2 more
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Genetic variants of fatty acid elongase 6 in Chinese Holstein cow
Gene, 2018In the dairy industry, genetic variants have contributed to the improvement of milk production traits. Fatty acid elongase 6 (ELOVL6), which elongates saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs), plays a distinct role in the balance of long-chain fatty acids composition in animals.
Si Chen +6 more
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3D Structure Modeling of a Transmembrane Protein, Fatty Acid Elongase
2010Fatty acid elongase is an enzyme responsible for fatty acid chain elongation, a key step in synthesis of long chain fatty acids, including polyunsaturated fatty acids (PUFAs). Currently, the increasing demand has raised the interest in obtaining these PUFAs from alternative sources, e.g. filamentous fungi that are more economical and sustainable.
Sansai Chumningan +4 more
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Biochemical Society Transactions, 2000
In order to elucidate the biosynthesis of longchain polyunsaturated fatty acids (PUFAs) in plants we searched for a cDNA encoding a Δ6-specific PUFA elongase from Physcomitrella patens which is known to contain high proportions of arachidonic acid (20:4 Δ5,8,11,14). An EST clone from P.
T K, Zank +3 more
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In order to elucidate the biosynthesis of longchain polyunsaturated fatty acids (PUFAs) in plants we searched for a cDNA encoding a Δ6-specific PUFA elongase from Physcomitrella patens which is known to contain high proportions of arachidonic acid (20:4 Δ5,8,11,14). An EST clone from P.
T K, Zank +3 more
openaire +2 more sources